Clinical Characteristics of T-Nonanaplastic Large-Cell Lymphoma and T-Anaplastic Large-Cell Lymphoma Patients
Parameter . | Non-ALCL-T (n = 228) (%) . | ALCL-T (n = 60) (%) . | P Value . |
---|---|---|---|
Age ≤60 yr | 60 | 75 | .04 |
Male | 68 | 73 | .4 |
Female | 32 | 26 | |
Stage | |||
I-II | 14 | 30 | .001 |
III-IV | 85 | 50 | |
B-symptoms | 48 | 56 | .2 |
PS >1 | 30 | 19 | .08 |
ENS >1 | 40 | 23 | .01 |
BM positive | 36 | 13 | .001 |
Bulk >10 cm | 28 | 19 | .1 |
Hepatomegaly | 23 | 15 | .1 |
Splenomegaly | 39 | 13 | .001 |
Skin lesions | 19 | 26 | .2 |
LDH >NI | 55 | 34 | .004 |
β2-microglobulin >NI | 55 | 32 | .01 |
Hemoglobin <10 g/dL | 21 | 18 | .5 |
Platelets <100 × 109/L | 7 | 11 | .3 |
Eosinophils ≥0.8 × 109/L | 15 | 5 | .1 |
Gammaglobulin >20 g/L | 10 | 0 | .001 |
IPI score*: | |||
0 factors | 7 | 39 | .001 |
1 factor | 15 | 24 | |
2 factor | 26 | 14 | |
≥3 factors | 51 | 22 |
Parameter . | Non-ALCL-T (n = 228) (%) . | ALCL-T (n = 60) (%) . | P Value . |
---|---|---|---|
Age ≤60 yr | 60 | 75 | .04 |
Male | 68 | 73 | .4 |
Female | 32 | 26 | |
Stage | |||
I-II | 14 | 30 | .001 |
III-IV | 85 | 50 | |
B-symptoms | 48 | 56 | .2 |
PS >1 | 30 | 19 | .08 |
ENS >1 | 40 | 23 | .01 |
BM positive | 36 | 13 | .001 |
Bulk >10 cm | 28 | 19 | .1 |
Hepatomegaly | 23 | 15 | .1 |
Splenomegaly | 39 | 13 | .001 |
Skin lesions | 19 | 26 | .2 |
LDH >NI | 55 | 34 | .004 |
β2-microglobulin >NI | 55 | 32 | .01 |
Hemoglobin <10 g/dL | 21 | 18 | .5 |
Platelets <100 × 109/L | 7 | 11 | .3 |
Eosinophils ≥0.8 × 109/L | 15 | 5 | .1 |
Gammaglobulin >20 g/L | 10 | 0 | .001 |
IPI score*: | |||
0 factors | 7 | 39 | .001 |
1 factor | 15 | 24 | |
2 factor | 26 | 14 | |
≥3 factors | 51 | 22 |
*Based on data from 261 PTCL and 1,433 BCL patients.