Characteristics of Patients
| . | CLB 1996 (n = 1,051) . | CLB 1997 (n = 312) . | ELYPSE 1 (n = 295) . | CLB-NHL (n = 149) . | Total (n = 1,807) . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of Patients . | % . | No. of Patients . | % . | No. of Patients . | % . | No. of Patients . | % . | No. . | % . | |
| Median age (range) | 55 (18-86) | 56 (18-85) | 58 (18-86) | 70 (27-93) | ||||||
| Age (yr) | ||||||||||
| <60 | 655 | 62 | 179 | 57 | 167* | 57 | 37 | 25 | 1,038 | 58 |
| ≥60 | 396 | 38 | 133 | 43 | 123* | 43 | 112 | 75 | 764 | 42 |
| Sex | ||||||||||
| F | 567 | 54 | 161 | 52 | 178 | 60 | 68 | 46 | 974 | 54 |
| M | 484 | 46 | 151 | 48 | 117 | 40 | 81 | 54 | 833 | 46 |
| Diagnostic | ||||||||||
| Carcinoma | ||||||||||
| Breast | 247 | 24 | 78 | 25 | 99 | 34 | 0 | 0 | 424 | 23 |
| Colon-rectum | 96 | 9 | 16 | 5 | 50 | 17 | 0 | 0 | 162 | 9 |
| Ovary | 90 | 9 | 14 | 5 | 32 | 11 | 0 | 0 | 136 | 8 |
| Head and neck | 103 | 10 | 20 | 6 | 20 | 7 | 0 | 0 | 143 | 8 |
| Other gastrointestinal | 112 | 11 | 18 | 5 | 11 | 4 | 0 | 0 | 141 | 8 |
| Lung cancer | 61 | 6 | 22 | 7 | 8 | 3 | 0 | 0 | 91 | 5 |
| Lymphoma | 93 | 9 | 37 | 12 | 21 | 7 | 149 | 100 | 300 | 17 |
| Bone and soft tissue sarcoma | 68 | 7 | 17 | 5 | 13 | 4 | 0 | 0 | 98 | 5 |
| Germ cells tumors | 32 | 3 | 15 | 5 | 7 | 2 | 0 | 0 | 54 | 3 |
| Others | 149 | 14 | 75 | 25 | 34 | 10 | 0 | 0 | 258 | 14 |
| High-risk chemotherapy-151 | ||||||||||
| Yes | 105 | 10 | 92 | 29 | 24 | 8 | 74 | 50 | 295 | 16 |
| No | 946 | 90 | 220 | 71 | 271 | 92 | 75 | 50 | 1,512 | 84 |
| Chemotherapy regimens | ||||||||||
| ACVBP/ECVBP | 14 | 1 | 14 | 4 | 4 | 1 | 74 | 50 | 106 | 6 |
| ADRIAMYCINE alone | 27 | 3 | 13 | 4 | 0 | 0 | 0 | 0 | 40 | 2 |
| CDDP-5FU | 85 | 8 | 15 | 5 | 16 | 5 | 0 | 0 | 116 | 6 |
| CDDP-NAV/CDDP-VP16 | 55 | 5 | 22 | 7 | 7 | 2 | 0 | 0 | 84 | 5 |
| DHAP | 24 | 2 | 7 | 2 | 0 | 0 | 0 | 0 | 31 | 2 |
| FAC/FEC/AC | 115 | 11 | 44 | 14 | 90 | 28 | 0 | 0 | 249 | 14 |
| FUFOL/LV5FU2 | 71 | 7 | 14 | 5 | 47 | 15 | 0 | 0 | 132 | 7 |
| MAID | 11 | 1 | 7 | 2 | 2 | 1 | 0 | 0 | 20 | 1 |
| mBACOD | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 10 | 15 | 1 |
| TAXANES | 124 | 12 | 29 | 9 | 29 | 9 | 0 | 0 | 182 | 10 |
| CHOP | 25 | 2 | 12 | 4 | 9 | 3 | 53 | 36 | 99 | 5 |
| BEP/EP | 30 | 3 | 17 | 5 | 7 | 2 | 0 | 0 | 54 | 3 |
| NAVELBINE alone | 74 | 7 | 15 | 5 | 0 | 0 | 0 | 0 | 89 | 5 |
| CAP/CEP/CP | 34 | 3 | 2 | 1 | 22 | 7 | 0 | 0 | 58 | 3 |
| Other | 362 | 34 | 101 | 36 | 71 | 24 | 7 | 5 | 541 | 30 |
| No. of chemotherapy course | ||||||||||
| 1 | 766-152 | 78 | 306 | 98 | 130 | 44 | 149 | 100 | 1,351 | 78 |
| ≥2 | 213-152 | 22 | 6 | 2 | 165 | 56 | 0 | 0 | 384 | 21 |
| Performance status | ||||||||||
| 0-1 | 881 | 84 | 250 | 80 | 252 | 85 | 103 | 69 | 1,486 | 82 |
| >1 | 170 | 16 | 62 | 20 | 43 | 15 | 46 | 31 | 321 | 18 |
| . | CLB 1996 (n = 1,051) . | CLB 1997 (n = 312) . | ELYPSE 1 (n = 295) . | CLB-NHL (n = 149) . | Total (n = 1,807) . | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of Patients . | % . | No. of Patients . | % . | No. of Patients . | % . | No. of Patients . | % . | No. . | % . | |
| Median age (range) | 55 (18-86) | 56 (18-85) | 58 (18-86) | 70 (27-93) | ||||||
| Age (yr) | ||||||||||
| <60 | 655 | 62 | 179 | 57 | 167* | 57 | 37 | 25 | 1,038 | 58 |
| ≥60 | 396 | 38 | 133 | 43 | 123* | 43 | 112 | 75 | 764 | 42 |
| Sex | ||||||||||
| F | 567 | 54 | 161 | 52 | 178 | 60 | 68 | 46 | 974 | 54 |
| M | 484 | 46 | 151 | 48 | 117 | 40 | 81 | 54 | 833 | 46 |
| Diagnostic | ||||||||||
| Carcinoma | ||||||||||
| Breast | 247 | 24 | 78 | 25 | 99 | 34 | 0 | 0 | 424 | 23 |
| Colon-rectum | 96 | 9 | 16 | 5 | 50 | 17 | 0 | 0 | 162 | 9 |
| Ovary | 90 | 9 | 14 | 5 | 32 | 11 | 0 | 0 | 136 | 8 |
| Head and neck | 103 | 10 | 20 | 6 | 20 | 7 | 0 | 0 | 143 | 8 |
| Other gastrointestinal | 112 | 11 | 18 | 5 | 11 | 4 | 0 | 0 | 141 | 8 |
| Lung cancer | 61 | 6 | 22 | 7 | 8 | 3 | 0 | 0 | 91 | 5 |
| Lymphoma | 93 | 9 | 37 | 12 | 21 | 7 | 149 | 100 | 300 | 17 |
| Bone and soft tissue sarcoma | 68 | 7 | 17 | 5 | 13 | 4 | 0 | 0 | 98 | 5 |
| Germ cells tumors | 32 | 3 | 15 | 5 | 7 | 2 | 0 | 0 | 54 | 3 |
| Others | 149 | 14 | 75 | 25 | 34 | 10 | 0 | 0 | 258 | 14 |
| High-risk chemotherapy-151 | ||||||||||
| Yes | 105 | 10 | 92 | 29 | 24 | 8 | 74 | 50 | 295 | 16 |
| No | 946 | 90 | 220 | 71 | 271 | 92 | 75 | 50 | 1,512 | 84 |
| Chemotherapy regimens | ||||||||||
| ACVBP/ECVBP | 14 | 1 | 14 | 4 | 4 | 1 | 74 | 50 | 106 | 6 |
| ADRIAMYCINE alone | 27 | 3 | 13 | 4 | 0 | 0 | 0 | 0 | 40 | 2 |
| CDDP-5FU | 85 | 8 | 15 | 5 | 16 | 5 | 0 | 0 | 116 | 6 |
| CDDP-NAV/CDDP-VP16 | 55 | 5 | 22 | 7 | 7 | 2 | 0 | 0 | 84 | 5 |
| DHAP | 24 | 2 | 7 | 2 | 0 | 0 | 0 | 0 | 31 | 2 |
| FAC/FEC/AC | 115 | 11 | 44 | 14 | 90 | 28 | 0 | 0 | 249 | 14 |
| FUFOL/LV5FU2 | 71 | 7 | 14 | 5 | 47 | 15 | 0 | 0 | 132 | 7 |
| MAID | 11 | 1 | 7 | 2 | 2 | 1 | 0 | 0 | 20 | 1 |
| mBACOD | 0 | 0 | 0 | 0 | 0 | 0 | 15 | 10 | 15 | 1 |
| TAXANES | 124 | 12 | 29 | 9 | 29 | 9 | 0 | 0 | 182 | 10 |
| CHOP | 25 | 2 | 12 | 4 | 9 | 3 | 53 | 36 | 99 | 5 |
| BEP/EP | 30 | 3 | 17 | 5 | 7 | 2 | 0 | 0 | 54 | 3 |
| NAVELBINE alone | 74 | 7 | 15 | 5 | 0 | 0 | 0 | 0 | 89 | 5 |
| CAP/CEP/CP | 34 | 3 | 2 | 1 | 22 | 7 | 0 | 0 | 58 | 3 |
| Other | 362 | 34 | 101 | 36 | 71 | 24 | 7 | 5 | 541 | 30 |
| No. of chemotherapy course | ||||||||||
| 1 | 766-152 | 78 | 306 | 98 | 130 | 44 | 149 | 100 | 1,351 | 78 |
| ≥2 | 213-152 | 22 | 6 | 2 | 165 | 56 | 0 | 0 | 384 | 21 |
| Performance status | ||||||||||
| 0-1 | 881 | 84 | 250 | 80 | 252 | 85 | 103 | 69 | 1,486 | 82 |
| >1 | 170 | 16 | 62 | 20 | 43 | 15 | 46 | 31 | 321 | 18 |