Association Between Pretransplant IFN-α for ≥6 Months and Mortality From Day 100 to Day 365 Posttransplant, Stratified According to Severity of Acute GVHD
| Acute GVHD Prednisone Response . | IFN-α 0-5 mo (no. died/total) . | IFN-α ≥6 mo (no. died/total) . | PValue (χ2 test) . |
|---|---|---|---|
| No prednisone | 2/33 (6%) | 1/11 (9%) | .7 |
| Prednisone-sensitive | 8.62 (13%) | 2/16 (13%) | 1 |
| Prednisone-dependent or refractory | 8/24 (33%) | 12/14 (86%) | .002 |
| Total | 18/119 (15%) | 15/41 (37%) | .003 |
| Acute GVHD Prednisone Response . | IFN-α 0-5 mo (no. died/total) . | IFN-α ≥6 mo (no. died/total) . | PValue (χ2 test) . |
|---|---|---|---|
| No prednisone | 2/33 (6%) | 1/11 (9%) | .7 |
| Prednisone-sensitive | 8.62 (13%) | 2/16 (13%) | 1 |
| Prednisone-dependent or refractory | 8/24 (33%) | 12/14 (86%) | .002 |
| Total | 18/119 (15%) | 15/41 (37%) | .003 |