Adoptively Transferred IL-2−/− T Cells Do Not Adversely Affect the Cellularity or Composition of Host Bone Marow
| Donor T Cells . | Cell No. × 106 * . | % of Mac-1+ . | %GR-1+ . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total . | Thy1.1 (host) . | Thy1.2 (donor) . | B220 . | Ter-119 . | Mac-1 . | Gr-1 . | Mac-1lo . | Mac-1hi . | Gr-1lo . | Gr-1hi . | |
| SPF IL-2+/+ | 18.1 ± 3.1 | 0.22 ± 0.1 | 0.7 ± 0.2 | 4.6 ± 1.1 | 7.0 ± 2.1 | 10.1 ± 2.3 | 7.0 ± 1.8 | 40 ± 5 | 45 ± 7 | 21 ± 5 | 26 ± 4 |
| SPF IL-2−/− | 19.8 ± 4.4 | 0.20 ± 0.2 | 0.5 ± 0.2 | 3.9 ± 1.0 | 6.2 ± 2.4 | 9.0 ± 2.5 | 6.0 ± 1.9 | 37 ± 6 | 41 ± 8 | 17 ± 9 | 23 ± 5 |
| Donor T Cells . | Cell No. × 106 * . | % of Mac-1+ . | %GR-1+ . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total . | Thy1.1 (host) . | Thy1.2 (donor) . | B220 . | Ter-119 . | Mac-1 . | Gr-1 . | Mac-1lo . | Mac-1hi . | Gr-1lo . | Gr-1hi . | |
| SPF IL-2+/+ | 18.1 ± 3.1 | 0.22 ± 0.1 | 0.7 ± 0.2 | 4.6 ± 1.1 | 7.0 ± 2.1 | 10.1 ± 2.3 | 7.0 ± 1.8 | 40 ± 5 | 45 ± 7 | 21 ± 5 | 26 ± 4 |
| SPF IL-2−/− | 19.8 ± 4.4 | 0.20 ± 0.2 | 0.5 ± 0.2 | 3.9 ± 1.0 | 6.2 ± 2.4 | 9.0 ± 2.5 | 6.0 ± 1.9 | 37 ± 6 | 41 ± 8 | 17 ± 9 | 23 ± 5 |
*Bone marrow was analyzed 6 weeks after adoptive transfer of T cells.