Summary of Clinical Features of Patients With WT1 Mutations
| Sample . | Age . | Diagnosis . | Cytogenetics . | Achieved CR . | Clinical Summary . |
|---|---|---|---|---|---|
| 58* | 33 | AML M1 | No clone | No | Died of refractory disease |
| 87 | 35 | Relapsed AML M0 | 47 XX +19 | — | Died of toxicity |
| 216* | 22 | AML M2 | No clone | No | Died of refractory disease |
| 232M* | 18 | AML M3 | Failed | — | Died of cerebral hemorrhage, d 8 |
| 146 | 17 | AML M3 | 47 XY t(15:17) +8, −21 | Yes | Died of disease after second relapse |
| 126 | 6 | T-ALL | Normal | Yes | Relapsed 21 months after diagnosis, still on treatment |
| 132* | 25 | Biphenotypic | Complex >80 | No | Died of refractory disease |
| 101 | 12 | AUL | del (6)(q2), del (11)(p1), add (11)(p1) | ?No | Died of disease 1 year after diagnosis |
| Sample . | Age . | Diagnosis . | Cytogenetics . | Achieved CR . | Clinical Summary . |
|---|---|---|---|---|---|
| 58* | 33 | AML M1 | No clone | No | Died of refractory disease |
| 87 | 35 | Relapsed AML M0 | 47 XX +19 | — | Died of toxicity |
| 216* | 22 | AML M2 | No clone | No | Died of refractory disease |
| 232M* | 18 | AML M3 | Failed | — | Died of cerebral hemorrhage, d 8 |
| 146 | 17 | AML M3 | 47 XY t(15:17) +8, −21 | Yes | Died of disease after second relapse |
| 126 | 6 | T-ALL | Normal | Yes | Relapsed 21 months after diagnosis, still on treatment |
| 132* | 25 | Biphenotypic | Complex >80 | No | Died of refractory disease |
| 101 | 12 | AUL | del (6)(q2), del (11)(p1), add (11)(p1) | ?No | Died of disease 1 year after diagnosis |
*See King-Underwood et al5 for further details.