Percentage of PNH Cells at Different Stages of Maturation
Patient . | Neutrophils . | CD34+/CD38+Cells . | CD34+/CD38− Cells . |
---|---|---|---|
PNH043 | |||
Pre | 96 | 50 | 0 |
Post | 94 | 87 | 91 |
PNH042 | |||
Pre | 97 | 29 | 7 |
Post | 96 | 90 | 88 |
PNH056 | |||
Pre | 50 | 47 | 0 |
Post | 55 | 68 | 51 |
PNH046 | |||
Pre | 79 | 78 | 71 |
Post | 76 | 80 | 73 |
Patient . | Neutrophils . | CD34+/CD38+Cells . | CD34+/CD38− Cells . |
---|---|---|---|
PNH043 | |||
Pre | 96 | 50 | 0 |
Post | 94 | 87 | 91 |
PNH042 | |||
Pre | 97 | 29 | 7 |
Post | 96 | 90 | 88 |
PNH056 | |||
Pre | 50 | 47 | 0 |
Post | 55 | 68 | 51 |
PNH046 | |||
Pre | 79 | 78 | 71 |
Post | 76 | 80 | 73 |
The figures represent the percentage of peripheral blood cells in each subgroup that are of PNH phenotype as defined by lack of CD59 expression. CD34+/CD38+ cells are more mature stem cells while CD34+/CD38− cells are more primitive. The results for steady-state blood (pre–G-CSF) and mobilized blood (post–G-CSF) are shown.