Patient Characteristics Before BMT (n = 41)
Male/female | 19/22 |
Age (yr) | 12 ± 3.1 |
Number of red blood cells units transfused before BMT | 188 ± 91 |
Years of transfusion-dependent life before BMT | 11 ± 1 |
Thalassemia status of BM donors (normal/trait) | 15/26 |
Serum ferritin ( μg/L) | 3,964 (2,761-5,246) |
Transferrin saturation (%) | 89 ± 17 |
AST* | 2.5 ± 1.7 |
ALT* | 4.4 ± 3.3 |
Knodell Index7 (41 liver biopsies) | 7.3 ± 3.3 |
Liver iron concentration mg/g dw (21 liver biopsies) | 24.3 (18.8–27.6) |
Male/female | 19/22 |
Age (yr) | 12 ± 3.1 |
Number of red blood cells units transfused before BMT | 188 ± 91 |
Years of transfusion-dependent life before BMT | 11 ± 1 |
Thalassemia status of BM donors (normal/trait) | 15/26 |
Serum ferritin ( μg/L) | 3,964 (2,761-5,246) |
Transferrin saturation (%) | 89 ± 17 |
AST* | 2.5 ± 1.7 |
ALT* | 4.4 ± 3.3 |
Knodell Index7 (41 liver biopsies) | 7.3 ± 3.3 |
Liver iron concentration mg/g dw (21 liver biopsies) | 24.3 (18.8–27.6) |
Multiple of upper limit of reference range. Values are expressed as mean ± SD or as median with a range (25 to 75 percentile).