Table 1.

Patient Characteristics Before BMT (n = 41)

 
Male/female 19/22 
Age (yr) 12 ± 3.1 
Number of red blood cells units transfused before BMT 188 ± 91 
Years of transfusion-dependent life before BMT 11 ± 1 
Thalassemia status of BM donors (normal/trait) 15/26 
Serum ferritin ( μg/L) 3,964 (2,761-5,246) 
Transferrin saturation (%) 89 ± 17 
AST* 2.5 ± 1.7 
ALT* 4.4 ± 3.3 
Knodell Index7 (41 liver biopsies) 7.3 ± 3.3 
Liver iron concentration mg/g dw (21 liver biopsies) 24.3 (18.8–27.6) 
 
Male/female 19/22 
Age (yr) 12 ± 3.1 
Number of red blood cells units transfused before BMT 188 ± 91 
Years of transfusion-dependent life before BMT 11 ± 1 
Thalassemia status of BM donors (normal/trait) 15/26 
Serum ferritin ( μg/L) 3,964 (2,761-5,246) 
Transferrin saturation (%) 89 ± 17 
AST* 2.5 ± 1.7 
ALT* 4.4 ± 3.3 
Knodell Index7 (41 liver biopsies) 7.3 ± 3.3 
Liver iron concentration mg/g dw (21 liver biopsies) 24.3 (18.8–27.6) 
*

Multiple of upper limit of reference range. Values are expressed as mean ± SD or as median with a range (25 to 75 percentile).

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