Concentration of Iron in Bile (μg/mL) After IP Administration of the Chelators
| Chelator Time (h) . | PBH (101) . | PMBH (107) . | PFBH (109) . | PFH (114) . | PTCH (115) . | DFO . |
|---|---|---|---|---|---|---|
| −2 | 0.39 ± 0.14 | 0.79 ± 0.21 | 0.49 ± 0.10 | 1.06 ± 0.38 | 0.37 ± 0.1 | 0.66 ± 0.18 |
| −1 | 0.35 ± 0.08 | 0.76 ± 0.21 | 0.70 ± 0.10 | 0.89 ± 0.38 | 0.67 ± 0.27 | 0.71 ± 0.13 |
| +1 | 30.10 ± 5.70 | 36.1 ± 13.8 | 88.50 ± 25.80 | 28.77 ± 8.48 | 39.50 ± 7.40 | 21.23 ± 2.34 |
| +2 | 39.30 ± 9.10 | 64.20 ± 10.30 | 46.90 ± 20.20 | 15.30 ± 2.84 | 81.30 ± 29.40 | 12.48 ± 7.52 |
| +3 | 32.00 ± 6.70 | 62.40 ± 7.50 | 85.60 ± 33.30 | 7.91 ± 3.29 | 58.80 ± 20.70 | 4.78 ± 4.53 |
| +4 | 20.10 ± 6.50 | 55.10 ± 9.30 | 1.60 ± 23.80 | 5.05 ± 2.89 | 34.80 ± 12.90 | 1.05 ± 0.48 |
| +5 | 10.60 ± 3.80 | 30.50 ± 8.10 | 86.60 ± 31.40 | 3.45 ± 2.05 | 26.70 ± 10.20 | 0.94 ± 0.59 |
| +6 | 3.60 ± 1.90 | 19.70 ± 5.30 | 25.20 ± 13.50 | 2.30 ± 1.49 | 13.80 ± 6.50 | 0.93 ± 0.50 |
| +7 | 1.80 ± 0.70 | 8.20 ± 3.30 | 19.80 ± 2.60 | 1.81 ± 0.64 | 2.80 ± 1.40 | — |
| 8 | 0.67 ± 0.22 | 3.20 ± 1.1 | 1.27 ± 0.53 | 1.60 ± 0.70 | — |
| Chelator Time (h) . | PBH (101) . | PMBH (107) . | PFBH (109) . | PFH (114) . | PTCH (115) . | DFO . |
|---|---|---|---|---|---|---|
| −2 | 0.39 ± 0.14 | 0.79 ± 0.21 | 0.49 ± 0.10 | 1.06 ± 0.38 | 0.37 ± 0.1 | 0.66 ± 0.18 |
| −1 | 0.35 ± 0.08 | 0.76 ± 0.21 | 0.70 ± 0.10 | 0.89 ± 0.38 | 0.67 ± 0.27 | 0.71 ± 0.13 |
| +1 | 30.10 ± 5.70 | 36.1 ± 13.8 | 88.50 ± 25.80 | 28.77 ± 8.48 | 39.50 ± 7.40 | 21.23 ± 2.34 |
| +2 | 39.30 ± 9.10 | 64.20 ± 10.30 | 46.90 ± 20.20 | 15.30 ± 2.84 | 81.30 ± 29.40 | 12.48 ± 7.52 |
| +3 | 32.00 ± 6.70 | 62.40 ± 7.50 | 85.60 ± 33.30 | 7.91 ± 3.29 | 58.80 ± 20.70 | 4.78 ± 4.53 |
| +4 | 20.10 ± 6.50 | 55.10 ± 9.30 | 1.60 ± 23.80 | 5.05 ± 2.89 | 34.80 ± 12.90 | 1.05 ± 0.48 |
| +5 | 10.60 ± 3.80 | 30.50 ± 8.10 | 86.60 ± 31.40 | 3.45 ± 2.05 | 26.70 ± 10.20 | 0.94 ± 0.59 |
| +6 | 3.60 ± 1.90 | 19.70 ± 5.30 | 25.20 ± 13.50 | 2.30 ± 1.49 | 13.80 ± 6.50 | 0.93 ± 0.50 |
| +7 | 1.80 ± 0.70 | 8.20 ± 3.30 | 19.80 ± 2.60 | 1.81 ± 0.64 | 2.80 ± 1.40 | — |
| 8 | 0.67 ± 0.22 | 3.20 ± 1.1 | 1.27 ± 0.53 | 1.60 ± 0.70 | — |