Table 4. Comparison of Stimulatory... | American Society of Hematology

Table 4.

Comparison of Stimulatory Activity of Oleic Acid and Linolenic Acid on Proliferation of LD Cells and P-HSCs

Fatty Acid	LD Cells		P-HSCs
	Linolenic Acid	Oleic Acid	Linolenic Acid		Oleic Acid
	MS-5	MS-5	MS-5	BM Ad. Cells	BM Ad. Cells
0.5 μg/mL	1.98 ± 0.29^4-150	1.59 ± 0.13^4-150	2.46 ± 0.36^4-150	3.02 ± 0.14^4-151	1.71 ± 0.04^4-150
1.0 μg/mL	1.47 ± 0.29^4-150	1.65 ± 0.18^4-151	2.98 ± 0.29^4-151	4.90 ± 0.04^4-151	1.83 ± 0.39^4-150
2.0 μg/mL	ND	ND	4.44 ± 0.55^4-151	ND	ND

Fatty Acid	LD Cells		P-HSCs
	Linolenic Acid	Oleic Acid	Linolenic Acid		Oleic Acid
	MS-5	MS-5	MS-5	BM Ad. Cells	BM Ad. Cells
0.5 μg/mL	1.98 ± 0.29^4-150	1.59 ± 0.13^4-150	2.46 ± 0.36^4-150	3.02 ± 0.14^4-151	1.71 ± 0.04^4-150
1.0 μg/mL	1.47 ± 0.29^4-150	1.65 ± 0.18^4-151	2.98 ± 0.29^4-151	4.90 ± 0.04^4-151	1.83 ± 0.39^4-150
2.0 μg/mL	ND	ND	4.44 ± 0.55^4-151	ND	ND

P-HSCs were cultured on 20 Gy-irradiated MS-5 cells or syngeneic bone marrow stromal cells in the presence of fatty acids, and cell proliferation was measured 10 to 14 days later. LD cells were also cultured on MS-5 cells in the presence of oleic acid or linolenic acid for 4 days. Data are mean ± SE.

F4-150

Different from control (P < .05).

F4-151

P < .005.

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