Detail of Therapies in 11 Children Who Developed MDS/AML
| Patient . | rhG-CSF . | CSA . | ALG . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | Duration of Use (mo) . | Relation to the Onset of MDS/AML . | Cumulative Dose (mg/kg) . | Average Dose (μg/kg/d) . | Duration of Use (mo) . | Interval to the Onset of MDS/AML (mo) . | Relation to the Onset of MDS/AML . | Cumulative Dose (g) . | Interval to the Onset of MDS/AML (mo) . |
| 1 | 73 | In use | 2.4 | 1.1 | 48 | 70 | 19 mo later | 246 | 74 |
| 2 | 32 | In use | 2.4 | 2.5 | 46 | 57 | 10 mo later | 241 | 60 |
| 3 | 26 | In use | 10.0 | 12.8 | 6 | 15 | 9 mo later | 25 | |
| 4 | 11 | In use | 7.9 | 23.9 | 13 | 13 | In use | 4 | 14 |
| 5 | 25 | 5 mo later | 8.6 | 11.5 | 25 | 25 | In use | 543 | |
| 6 | 32 | In use | 9.7 | 9.0 | 3 | 25 | 22 mo later | 15 | 34 |
| 7 | 12 | In use | 8.2 | 17.0 | 4 | 8 | 4 mo later | 8 | |
| 8 | 15 | In use | 3.0 | 4.8 | 4 | 14 | 10 mo later | 19 | 4 |
| 9 | 22 | In use | 8.7 | 13.2 | 5 | 16 | 11 mo later | 13 | 14 |
| 10 | 22 | In use | 8.7 | 17.5 | 6 | 16 | 10 mo later | 17 | |
| 11 | 25 | In use | 4.7 | 6.3 | 6 | 24 | 18 mo later | 16 | |
| Patient . | rhG-CSF . | CSA . | ALG . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | Duration of Use (mo) . | Relation to the Onset of MDS/AML . | Cumulative Dose (mg/kg) . | Average Dose (μg/kg/d) . | Duration of Use (mo) . | Interval to the Onset of MDS/AML (mo) . | Relation to the Onset of MDS/AML . | Cumulative Dose (g) . | Interval to the Onset of MDS/AML (mo) . |
| 1 | 73 | In use | 2.4 | 1.1 | 48 | 70 | 19 mo later | 246 | 74 |
| 2 | 32 | In use | 2.4 | 2.5 | 46 | 57 | 10 mo later | 241 | 60 |
| 3 | 26 | In use | 10.0 | 12.8 | 6 | 15 | 9 mo later | 25 | |
| 4 | 11 | In use | 7.9 | 23.9 | 13 | 13 | In use | 4 | 14 |
| 5 | 25 | 5 mo later | 8.6 | 11.5 | 25 | 25 | In use | 543 | |
| 6 | 32 | In use | 9.7 | 9.0 | 3 | 25 | 22 mo later | 15 | 34 |
| 7 | 12 | In use | 8.2 | 17.0 | 4 | 8 | 4 mo later | 8 | |
| 8 | 15 | In use | 3.0 | 4.8 | 4 | 14 | 10 mo later | 19 | 4 |
| 9 | 22 | In use | 8.7 | 13.2 | 5 | 16 | 11 mo later | 13 | 14 |
| 10 | 22 | In use | 8.7 | 17.5 | 6 | 16 | 10 mo later | 17 | |
| 11 | 25 | In use | 4.7 | 6.3 | 6 | 24 | 18 mo later | 16 | |