Effect of Phosphorothioate ODNs on BV173
| ODN . | 3′ End . | Cell Counts After 72 Hours . | |
|---|---|---|---|
| . | . | (% of Control ± SD) . | |
| . | . | 2.5% NHS . | 10% FCS . |
| PS1 | GAT | 83 ± 10 | 11 ± 1 |
| PS2 | GCG | 84 ± 11 | 59 ± 13 |
| PS3 | CTT | 19 ± 6 | |
| PS4 | GCG | 59 ± 10 | |
| PS5 | GCG | 59 ± 1 | |
| PS6 | GAT | 18 ± 0 | |
| ODN . | 3′ End . | Cell Counts After 72 Hours . | |
|---|---|---|---|
| . | . | (% of Control ± SD) . | |
| . | . | 2.5% NHS . | 10% FCS . |
| PS1 | GAT | 83 ± 10 | 11 ± 1 |
| PS2 | GCG | 84 ± 11 | 59 ± 13 |
| PS3 | CTT | 19 ± 6 | |
| PS4 | GCG | 59 ± 10 | |
| PS5 | GCG | 59 ± 1 | |
| PS6 | GAT | 18 ± 0 | |
BV173 cell viability expressed as a percentage of control cell counts 72 hours after a single addition of phosphorothioate ODN at a concentration of 10 μmol/L, in RPMI 1640 containing 2.5% NHS or 10% FCS. Data are expressed as the mean of at least three experiments ± SD.