Table 2.

Two-Point Lod Score for the Microsatellite in the β-Globin Gene Cluster and the Chromosome 6q Markers in the Combined Pedigree and the Two Halves, Pedigrees A and B

MarkerLod Score at Recombination Fraction (θ) of
.00.01.05.10.20.30.40
β cluster 
Combined −infini −2.17 −0.88 −0.42 −0.11 −0.03 −0.02 
Pedigree A −infini −2.51 −1.18 −0.67 −0.27 −0.11 −0.04 
Pedigree B 0.35 0.34 0.30 0.25 0.16 0.08 0.02 
D6S408 
Combined −4.24 −2.40 −0.76 −0.15 0.21 0.22 0.12 
Pedigree A −3.05 −1.08 −0.06 0.27 0.38 0.28 0.14 
Pedigree B −3.34 −1.94 −0.84 −0.38 −0.04 0.04 0.02 
D6S407 
Combined −infini −4.77 −2.93 −1.94 −0.83 −0.28 −0.05 
Pedigree A −infini −3.62 −2.10 −1.37 −0.56 −0.17 −0.02 
Pedigree B −3.06 −1.92 −1.01 −0.55 −0.15 −0.02 0.01 
D6S262 
Combined −infini −4.41 −1.93 −0.89 −0.06 0.15 0.11 
Pedigree A −infini −3.01 −1.21 −0.43 0.13 0.22 0.12 
Pedigree B −5.30 −2.17 −0.90 −0.42 −0.07 0.02 0.02 
D6S435 
Combined −infini −5.31 −2.53 −1.33 −0.37 −0.07 −0.00 
Pedigree A −infini −3.23 −1.34 −0.57 −0.03 0.06 0.03 
Pedigree B −7.48 −2.85 −1.37 −0.74 −0.22 −0.04 0.00 
D6S457 
Combined −5.89 −2.33 −1.39 −0.82 −0.18 0.05 0.07 
Pedigree A −0.25 −0.26 −0.20 −0.05 0.16 0.19 0.10 
 
Pedigree B −7.44 −2.85 −1.37 −0.74 −0.22 −0.04 0.00 
D6S413 
Combined −infini −3.06 −2.12 −1.49 −0.71 −0.28 −0.07 
Pedigree A −infini −2.83 −1.94 −1.36 −0.64 −0.25 −0.06 
Pedigree B −2.63 −1.58 −0.89 −0.58 −0.26 −0.11 −0.03 
D6S472 
Combined −infini −3.35 −1.79 −1.11 −0.44 −0.12 0.00 
Pedigree A −infini −2.24 −1.37 −0.85 −0.32 −0.08 0.01 
Pedigree B −2.70 −1.38 −0.72 −0.43 −0.17 −0.06 −0.01 
D6S975 
Combined −infini −4.29 −2.01 −1.02 −0.23 0.02 0.03 
Pedigree A −infini −2.22 −0.82 −0.26 0.12 0.15 0.06 
Pedigree B −5.00 −1.49 −0.66 −0.30 −0.03 0.04 0.02 
D6S976/D6S270 
Combined −5.69 −1.35 −0.00 0.49 0.72 0.58 0.30 
Pedigree A −0.05 0.73 1.19 1.25 1.06 0.72 0.33 
Pedigree B −5.04 −1.49 −0.66 −0.30 −0.03 0.04 0.02 
D6S292 
Combined −4.14 −2.46 −1.38 −0.76 −0.12 0.12 0.13 
Pedigree A −1.30 −1.21 −0.86 −0.47 0.02 0.17 0.14 
Pedigree B −2.88 −1.54 −0.82 −0.50 −0.20 −0.07 −0.01 
MarkerLod Score at Recombination Fraction (θ) of
.00.01.05.10.20.30.40
β cluster 
Combined −infini −2.17 −0.88 −0.42 −0.11 −0.03 −0.02 
Pedigree A −infini −2.51 −1.18 −0.67 −0.27 −0.11 −0.04 
Pedigree B 0.35 0.34 0.30 0.25 0.16 0.08 0.02 
D6S408 
Combined −4.24 −2.40 −0.76 −0.15 0.21 0.22 0.12 
Pedigree A −3.05 −1.08 −0.06 0.27 0.38 0.28 0.14 
Pedigree B −3.34 −1.94 −0.84 −0.38 −0.04 0.04 0.02 
D6S407 
Combined −infini −4.77 −2.93 −1.94 −0.83 −0.28 −0.05 
Pedigree A −infini −3.62 −2.10 −1.37 −0.56 −0.17 −0.02 
Pedigree B −3.06 −1.92 −1.01 −0.55 −0.15 −0.02 0.01 
D6S262 
Combined −infini −4.41 −1.93 −0.89 −0.06 0.15 0.11 
Pedigree A −infini −3.01 −1.21 −0.43 0.13 0.22 0.12 
Pedigree B −5.30 −2.17 −0.90 −0.42 −0.07 0.02 0.02 
D6S435 
Combined −infini −5.31 −2.53 −1.33 −0.37 −0.07 −0.00 
Pedigree A −infini −3.23 −1.34 −0.57 −0.03 0.06 0.03 
Pedigree B −7.48 −2.85 −1.37 −0.74 −0.22 −0.04 0.00 
D6S457 
Combined −5.89 −2.33 −1.39 −0.82 −0.18 0.05 0.07 
Pedigree A −0.25 −0.26 −0.20 −0.05 0.16 0.19 0.10 
 
Pedigree B −7.44 −2.85 −1.37 −0.74 −0.22 −0.04 0.00 
D6S413 
Combined −infini −3.06 −2.12 −1.49 −0.71 −0.28 −0.07 
Pedigree A −infini −2.83 −1.94 −1.36 −0.64 −0.25 −0.06 
Pedigree B −2.63 −1.58 −0.89 −0.58 −0.26 −0.11 −0.03 
D6S472 
Combined −infini −3.35 −1.79 −1.11 −0.44 −0.12 0.00 
Pedigree A −infini −2.24 −1.37 −0.85 −0.32 −0.08 0.01 
Pedigree B −2.70 −1.38 −0.72 −0.43 −0.17 −0.06 −0.01 
D6S975 
Combined −infini −4.29 −2.01 −1.02 −0.23 0.02 0.03 
Pedigree A −infini −2.22 −0.82 −0.26 0.12 0.15 0.06 
Pedigree B −5.00 −1.49 −0.66 −0.30 −0.03 0.04 0.02 
D6S976/D6S270 
Combined −5.69 −1.35 −0.00 0.49 0.72 0.58 0.30 
Pedigree A −0.05 0.73 1.19 1.25 1.06 0.72 0.33 
Pedigree B −5.04 −1.49 −0.66 −0.30 −0.03 0.04 0.02 
D6S292 
Combined −4.14 −2.46 −1.38 −0.76 −0.12 0.12 0.13 
Pedigree A −1.30 −1.21 −0.86 −0.47 0.02 0.17 0.14 
Pedigree B −2.88 −1.54 −0.82 −0.50 −0.20 −0.07 −0.01 
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