Table 1. IRP Activity and Ft Content in... | American Society of Hematology

Table 1.

IRP Activity and Ft Content in Monocytes in Relation to Iron Status

	No.	Serum Iron	Transferrin Saturation	Serum Ft	Monocyte Ft	IRP Activity
		μg/dL	%	μg/L	ng/mg Protein	pmol/mg Protein
Controls	28	88 ± 29	19 ± 8	31 ± 32	611 ± 427	0.62 ± 0.18
GH untreated	16	173 ± 56^*	80 ± 25^†	2,249 ± 1,967^†	1,261 ± 763^*	0.95 ± 0.15^†
GH treated	17	133 ± 68^*	50 ± 30^†	251 ± 229^†	637 ± 312	0.63 ± 0.19
SH	5	154 ± 46^*	59 ± 18^†	1,446 ± 1,039^†	1,204 ± 433^*	0.15 ± 0.04^†

	No.	Serum Iron	Transferrin Saturation	Serum Ft	Monocyte Ft	IRP Activity
		μg/dL	%	μg/L	ng/mg Protein	pmol/mg Protein
Controls	28	88 ± 29	19 ± 8	31 ± 32	611 ± 427	0.62 ± 0.18
GH untreated	16	173 ± 56^*	80 ± 25^†	2,249 ± 1,967^†	1,261 ± 763^*	0.95 ± 0.15^†
GH treated	17	133 ± 68^*	50 ± 30^†	251 ± 229^†	637 ± 312	0.63 ± 0.19
SH	5	154 ± 46^*	59 ± 18^†	1,446 ± 1,039^†	1,204 ± 433^*	0.15 ± 0.04^†

Analysis of serum iron indexes was performed as described in Materials and Methods. Monocyte Ft was measured by a radioimmunoassay based on an antihuman liver Ft antibody. IRP activity was determined by liquid scintillation counting of regions of the gels corresponding to the IRE/IRP complexes as reported in Materials and Methods. All values represent mean ± SD.

P < .05 v controls.

†

P < .001.

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