Table 3.

Combination index values for apoptotic effects of AraC and Nutlin-3a




ED50

ED75

ED90

ED95

Averaged CI*
OCI-AML-3   0.58   0.48   0.41   0.37   0.46  
MOLM-13   0.80   0.13   0.04   0.02   0.25  
Primary AML no. 1   0.76   0.38   0.22   0.16   0.38  
Primary AML no. 2
 
0.30
 
0.30
 
0.30
 
0.30
 
0.30
 



ED50

ED75

ED90

ED95

Averaged CI*
OCI-AML-3   0.58   0.48   0.41   0.37   0.46  
MOLM-13   0.80   0.13   0.04   0.02   0.25  
Primary AML no. 1   0.76   0.38   0.22   0.16   0.38  
Primary AML no. 2
 
0.30
 
0.30
 
0.30
 
0.30
 
0.30
 
*

The averaged combination index (CI) values were calculated from the ED50, ED75, ED90, and ED95.

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