Prognostic factors for survival in patients with cGVHD: univariate analysis
Patients with chronic GVHD, N = 124 . | Kaplan-Meier survival probability at 3 years . | 95% CI . | Hazard ratio . | P . | Favorable factors . |
|---|---|---|---|---|---|
| Treatment arm | |||||
| M/C | 0.58 | 0.45-0.70 | 0.78 | .29 | NA |
| TCD | 0.51 | 0.38-0.64 | 1.00 | NA | NA |
| Performance status at cGVHD diagnosis | Performance status of 80-100 | ||||
| Less than 80 | 0.34 | 0.20-0.48 | 2.66 | < .01 | NA |
| Greater than or equal to 80 | 0.68 | 0.57-0.80 | 1.00 | NA | NA |
| Platelet count at cGVHD diagnosis | Platelet count ≥ 100 000/μL | ||||
| Less than 100 000 | 0.41 | 0.28-0.55 | 2.41 | < .01 | NA |
| Greater than or equal to 100 000 | 0.71 | 0.59-0.83 | 1.00 | NA | NA |
| Prior acute GVHD | Acute GVHD grade 0 or 1 | ||||
| Grades II-IV | 0.45 | 0.32-0.58 | 1.84 | .02 | NA |
| 0 or 1 | 0.65 | 0.52-0.77 | 1.00 | NA | NA |
| HLA match | 6 of 6 HLA match | ||||
| 6 of 6 | 0.58 | 0.48-0.69 | 0.59 | .06 | NA |
| 5 of 6 | 0.42 | 0.23-0.60 | 1.00 | NA | NA |
| Risk status | Good risk status | ||||
| Poor | 0.38 | 0.17-0.58 | 2.04 | .02 | NA |
| Good | 0.58 | 0.48-0.68 | 1.00 | NA | NA |
| Recipient CMV serostatus | Seronegative | ||||
| Negative | 0.63 | 0.52-0.75 | 0.60 | .05 | NA |
| Positive | 0.42 | 0.28-0.57 | 1.00 | NA | NA |
Patients with chronic GVHD, N = 124 . | Kaplan-Meier survival probability at 3 years . | 95% CI . | Hazard ratio . | P . | Favorable factors . |
|---|---|---|---|---|---|
| Treatment arm | |||||
| M/C | 0.58 | 0.45-0.70 | 0.78 | .29 | NA |
| TCD | 0.51 | 0.38-0.64 | 1.00 | NA | NA |
| Performance status at cGVHD diagnosis | Performance status of 80-100 | ||||
| Less than 80 | 0.34 | 0.20-0.48 | 2.66 | < .01 | NA |
| Greater than or equal to 80 | 0.68 | 0.57-0.80 | 1.00 | NA | NA |
| Platelet count at cGVHD diagnosis | Platelet count ≥ 100 000/μL | ||||
| Less than 100 000 | 0.41 | 0.28-0.55 | 2.41 | < .01 | NA |
| Greater than or equal to 100 000 | 0.71 | 0.59-0.83 | 1.00 | NA | NA |
| Prior acute GVHD | Acute GVHD grade 0 or 1 | ||||
| Grades II-IV | 0.45 | 0.32-0.58 | 1.84 | .02 | NA |
| 0 or 1 | 0.65 | 0.52-0.77 | 1.00 | NA | NA |
| HLA match | 6 of 6 HLA match | ||||
| 6 of 6 | 0.58 | 0.48-0.69 | 0.59 | .06 | NA |
| 5 of 6 | 0.42 | 0.23-0.60 | 1.00 | NA | NA |
| Risk status | Good risk status | ||||
| Poor | 0.38 | 0.17-0.58 | 2.04 | .02 | NA |
| Good | 0.58 | 0.48-0.68 | 1.00 | NA | NA |
| Recipient CMV serostatus | Seronegative | ||||
| Negative | 0.63 | 0.52-0.75 | 0.60 | .05 | NA |
| Positive | 0.42 | 0.28-0.57 | 1.00 | NA | NA |
NA indicates not applicable.