Cause of death in allo-HSCT recipients challenged with tumor cells determined by bioluminescence and/or histopathologic analysis of liver and spleen
. | Tumor . | GVHD . | N/A . |
|---|---|---|---|
| Experiment A | |||
| P815 | 4/4 | 0/4 | 0/4 |
| P815 + WT | 7/10 | 0/10 | 3/10 |
| P815 + ICOS-/- | 6/10 | 0/10 | 4/10 |
| Experiment B | |||
| A20 | 8/8 | 0/8 | 0/8 |
| A20 + WT | 1/16 | 3/16 | 8/16 |
| A20 + ICOS-/- | 4/16 | 1/16 | 9/16 |
| Experiment C | |||
| A20-TGL | 4/4 | 0/4 | 0/4 |
| A20-TGL + WT | 0/10 | 3/10 | 5/10 |
| A20-TGL + ICOS-/- | 4/10 | 1/10 | 0/10 |
. | Tumor . | GVHD . | N/A . |
|---|---|---|---|
| Experiment A | |||
| P815 | 4/4 | 0/4 | 0/4 |
| P815 + WT | 7/10 | 0/10 | 3/10 |
| P815 + ICOS-/- | 6/10 | 0/10 | 4/10 |
| Experiment B | |||
| A20 | 8/8 | 0/8 | 0/8 |
| A20 + WT | 1/16 | 3/16 | 8/16 |
| A20 + ICOS-/- | 4/16 | 1/16 | 9/16 |
| Experiment C | |||
| A20-TGL | 4/4 | 0/4 | 0/4 |
| A20-TGL + WT | 0/10 | 3/10 | 5/10 |
| A20-TGL + ICOS-/- | 4/10 | 1/10 | 0/10 |
N/A indicates not analyzed due to tissue necrosis.