Laboratory features at the time of diagnosis and clinical features in Japanese patients with WHO-RA and RCMD classified according to the WHO criteria
. | WHO-RA, n = 96 . | RCMD, n = 32 . | P . |
---|---|---|---|
Sex, male/female | 53/43 | 15/17 | .41 |
Age, y | 55 (12-86) | 66 (16-88) | .038 |
Neutrophil count, × 109/L | 1.62 (0.26-4.69) | 1.28 (0.05-10.24) | .76 |
Hemoglobin concentration, g/L | 87 (30-143) | 71 (25-140) | .094 |
Platelet count, × 109/L | 38 (4-246) | 127 (13-390) | .026 |
2- or 3-lineage cytopenias, %* | 67 | 75 | .38 |
Abnormal karyotype, % | 24 | 36 | .26 |
Median survival, mo | 176 | 52 | .023 |
. | WHO-RA, n = 96 . | RCMD, n = 32 . | P . |
---|---|---|---|
Sex, male/female | 53/43 | 15/17 | .41 |
Age, y | 55 (12-86) | 66 (16-88) | .038 |
Neutrophil count, × 109/L | 1.62 (0.26-4.69) | 1.28 (0.05-10.24) | .76 |
Hemoglobin concentration, g/L | 87 (30-143) | 71 (25-140) | .094 |
Platelet count, × 109/L | 38 (4-246) | 127 (13-390) | .026 |
2- or 3-lineage cytopenias, %* | 67 | 75 | .38 |
Abnormal karyotype, % | 24 | 36 | .26 |
Median survival, mo | 176 | 52 | .023 |
Values for presentation characteristics are given as median and range (in parentheses) where applicable.
Cytopenia according to IPSS: hemoglobin concentration less than 100 g/L, absolute neutrophil count less than 1.5 × 109/L, platelet count less than 100 × 109/L.