Table 1.

Laboratory features at the time of diagnosis and clinical features in patients with RA classified according to the FAB criteria




Japan, n = 131

Germany, n = 597

P
Sex, male/female   70/61   309/288   .73  
Age, y   57 (12-88)   71 (7-93)   < .001  
Neutrophil count, × 109/L   1.58 (0.05-10.24)   1.98 (0.06-23.00)   < .001  
Hemoglobin concentration, g/L   84 (25-143)   94 (30-169)   .002  
Platelet count, × 109/L   41 (4-390)   127 (2-1540)   < .001  
2- or 3-lineage cytopenias, %*  68   39   < .001  
Abnormal karyotype, %   29   53   < .001  
Median survival, mo
 
175
 
40
 
< .001
 



Japan, n = 131

Germany, n = 597

P
Sex, male/female   70/61   309/288   .73  
Age, y   57 (12-88)   71 (7-93)   < .001  
Neutrophil count, × 109/L   1.58 (0.05-10.24)   1.98 (0.06-23.00)   < .001  
Hemoglobin concentration, g/L   84 (25-143)   94 (30-169)   .002  
Platelet count, × 109/L   41 (4-390)   127 (2-1540)   < .001  
2- or 3-lineage cytopenias, %*  68   39   < .001  
Abnormal karyotype, %   29   53   < .001  
Median survival, mo
 
175
 
40
 
< .001
 

Values for presentation characteristics are given as median and range (in parentheses) where applicable.

*

Cytopenia according to IPSS: hemoglobin concentration less than 100 g/L, absolute neutrophil count less than 1.5 × 109/L, platelet count less than 100 × 109/L.

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