Stem cell engraftment-related hematologic and infectious characteristics and adverse events during immediate posttransplantation period in 28 patients with SLE-related APS
Patient no. . | ANC above 0.5×109/L, d after transplantation . | Platelet count above 20×109/L, d after transplantation . | No. RBC units . | No. platelet units . | Time in hospital, d . | Infections during hospitalization . | Dialysis . | Intubation . |
|---|---|---|---|---|---|---|---|---|
| D-APS | ||||||||
| 1 | 8 | 0* | 6 | 4 SDU | 21 | None | No | No |
| 2 | 9 | 17 | 5 | 8 SDU | 10 | None | No | No |
| 3 | 10 | 12 | 4 | 7 SDU | 19 | None | No | No |
| 4 | 8 | 7 | 3 | 3 SDU | 26 | None | No | No |
| 5 | 8 | 7 | 3 | 2 SDU | 19 | None | No | No |
| 6 | 13 | 13 | 6 | 9 SDU + 12 RDU | 20 | None | Enrolled on HD | No |
| 7 | 10 | 13 | 6 | 10 SDU | 19 | MRSA bacteremia (catheter related) | No | No |
| 8 | 11 | 13 | 6 | 10 SDU | 20 | CMV antigenemia | Enrolled on HD | No |
| 9 | 8 | 8 | 3 | 3 SDU | 18 | None | No | No |
| 10 | 10 | 11 | 5 | 7 SDU + 5 RDU | 18 | Candida peritonitis (PD catheter related) | Enrolled on PD | No |
| 11 | 10 | 14 | 8 | 9 SDU + 5 RDU | 21 | None | No | No |
| 12 | 9 | 10 | 9 | 7 SDU + 6 RDU | 21 | None | No | No |
| 13 | 8 | 0† | 4 | 0 | 18 | Staphylococcus aureus UTI | No | No |
| 14 | 11 | 22 | 15 | 7 SDU + 35 RDU | 31 | Klebsiella pneumoniae bacteremia and pneumonia, Candida glabrata fungemia, Enterococcus faecalis UTI | No | Yes |
| 15 | 9 | 10 | 10 | 6 SDU | 17 | None | No | No |
| 16 | 10 | 14 | 6 | 5 SDU + 15 RDU | 31 | MRSA and VRE bacteremia, HSV rash | No | No |
| 17 | 9 | 11 | 0 | 5 SDU + 5 RDU | 18 | None | No | No |
| 18 | 9 | 11 | 5 | 2 SDU | 17 | None | No | No |
| 19 | 9 | 13 | 5 | 6 SDU | 11 | HSV stomatitis, Clostridium difficile colitis | No | No |
| 20 | 11 | 13 | 6 | 11 SDU + 12 RDU | 21 | None | No | No |
| P-APS | ||||||||
| 1 | 10 | 12 | 5 | 5 SDU | 19 | None | No | No |
| 2 | 9 | 10 | 2 | 9 SDU | 19 | Salmonella enterocolitis | No | No |
| 3 | 7 | 0* | 1 | 0 | 16 | None | No | No |
| 4 | 9 | 10 | 4 | 14 SDU | 17 | None | No | No |
| 5 | 11 | 11 | 7 | 7 SDU | 18 | Streptococcus sanguis bacteremia | No | No |
| 6 | 8 | 9 | 2 | 0 | 17 | None | No | No |
| 7 | 9 | 15 | 4 | 11 RDU | 22 | None | No | No |
| 8 | 8 | 0‡ | 4 | 0 | 17 | None | No | No |
| Average | 9 | 12 | 5 | 6 SDU + 4 RDU | 20 | NA | NA | NA |
Patient no. . | ANC above 0.5×109/L, d after transplantation . | Platelet count above 20×109/L, d after transplantation . | No. RBC units . | No. platelet units . | Time in hospital, d . | Infections during hospitalization . | Dialysis . | Intubation . |
|---|---|---|---|---|---|---|---|---|
| D-APS | ||||||||
| 1 | 8 | 0* | 6 | 4 SDU | 21 | None | No | No |
| 2 | 9 | 17 | 5 | 8 SDU | 10 | None | No | No |
| 3 | 10 | 12 | 4 | 7 SDU | 19 | None | No | No |
| 4 | 8 | 7 | 3 | 3 SDU | 26 | None | No | No |
| 5 | 8 | 7 | 3 | 2 SDU | 19 | None | No | No |
| 6 | 13 | 13 | 6 | 9 SDU + 12 RDU | 20 | None | Enrolled on HD | No |
| 7 | 10 | 13 | 6 | 10 SDU | 19 | MRSA bacteremia (catheter related) | No | No |
| 8 | 11 | 13 | 6 | 10 SDU | 20 | CMV antigenemia | Enrolled on HD | No |
| 9 | 8 | 8 | 3 | 3 SDU | 18 | None | No | No |
| 10 | 10 | 11 | 5 | 7 SDU + 5 RDU | 18 | Candida peritonitis (PD catheter related) | Enrolled on PD | No |
| 11 | 10 | 14 | 8 | 9 SDU + 5 RDU | 21 | None | No | No |
| 12 | 9 | 10 | 9 | 7 SDU + 6 RDU | 21 | None | No | No |
| 13 | 8 | 0† | 4 | 0 | 18 | Staphylococcus aureus UTI | No | No |
| 14 | 11 | 22 | 15 | 7 SDU + 35 RDU | 31 | Klebsiella pneumoniae bacteremia and pneumonia, Candida glabrata fungemia, Enterococcus faecalis UTI | No | Yes |
| 15 | 9 | 10 | 10 | 6 SDU | 17 | None | No | No |
| 16 | 10 | 14 | 6 | 5 SDU + 15 RDU | 31 | MRSA and VRE bacteremia, HSV rash | No | No |
| 17 | 9 | 11 | 0 | 5 SDU + 5 RDU | 18 | None | No | No |
| 18 | 9 | 11 | 5 | 2 SDU | 17 | None | No | No |
| 19 | 9 | 13 | 5 | 6 SDU | 11 | HSV stomatitis, Clostridium difficile colitis | No | No |
| 20 | 11 | 13 | 6 | 11 SDU + 12 RDU | 21 | None | No | No |
| P-APS | ||||||||
| 1 | 10 | 12 | 5 | 5 SDU | 19 | None | No | No |
| 2 | 9 | 10 | 2 | 9 SDU | 19 | Salmonella enterocolitis | No | No |
| 3 | 7 | 0* | 1 | 0 | 16 | None | No | No |
| 4 | 9 | 10 | 4 | 14 SDU | 17 | None | No | No |
| 5 | 11 | 11 | 7 | 7 SDU | 18 | Streptococcus sanguis bacteremia | No | No |
| 6 | 8 | 9 | 2 | 0 | 17 | None | No | No |
| 7 | 9 | 15 | 4 | 11 RDU | 22 | None | No | No |
| 8 | 8 | 0‡ | 4 | 0 | 17 | None | No | No |
| Average | 9 | 12 | 5 | 6 SDU + 4 RDU | 20 | NA | NA | NA |
ANC indicates absolute neutrophil count; SDU, single donor units; RDU, random donor units; HD, hemodialysis; MRSA, methicillin-resistant Staphylococcus aureus; CMV, cytomegalovirus; PD, peritoneal dialysis; UTI, urinary tract infection; VRE, vancomycin-resistant enterococcus; HSV, herpes simplex virus. Other abbreviations are explained in the text and Table 1.
Platelet counts never below 20×109/L.
Platelet count never below 75×109/L.
Platelet count never below 30×109/L.