Rolling velocity of CHO cells expressing GP Ibα mutant
. | 2.5 dyne/cm2 . | 10 dyne/cm2 . | 20 dyne/cm2 . |
|---|---|---|---|
| CHOαβ9 | 107 ± 34 | 180 ± 54 | 221 ± 67 |
| His37Ala | 153 ± 70 | 302 ± 94 | 517 ± 109 |
| Glu40Ala | 159 ± 72 | 223 ± 77 | 378 ± 98 |
| Asp83Ala | 110 ± 41 | 173 ± 46 | 214 ± 75 |
| His86Ala | 73 ± 22 | 136 ± 37 | 178 ± 30 |
| Asp106Ala | 133 ± 48 | 309 ± 92 | 373 ± 77 |
| Glu128Ala | No adhesion | No adhesion | No adhesion |
| Lys137Ala | 121 ± 38 | 260 ± 80 | 457 ± 93 |
| Lys152Ala | 142 ± 49 | 260 ± 93 | 314 ± 85 |
| Glu162Ala | 146 ± 76 | No adhesion | No adhesion |
| Asp175Ala | No adhesion | No adhesion | No adhesion |
| Lys189Ala | 142 ± 48 | No adhesion | No adhesion |
. | 2.5 dyne/cm2 . | 10 dyne/cm2 . | 20 dyne/cm2 . |
|---|---|---|---|
| CHOαβ9 | 107 ± 34 | 180 ± 54 | 221 ± 67 |
| His37Ala | 153 ± 70 | 302 ± 94 | 517 ± 109 |
| Glu40Ala | 159 ± 72 | 223 ± 77 | 378 ± 98 |
| Asp83Ala | 110 ± 41 | 173 ± 46 | 214 ± 75 |
| His86Ala | 73 ± 22 | 136 ± 37 | 178 ± 30 |
| Asp106Ala | 133 ± 48 | 309 ± 92 | 373 ± 77 |
| Glu128Ala | No adhesion | No adhesion | No adhesion |
| Lys137Ala | 121 ± 38 | 260 ± 80 | 457 ± 93 |
| Lys152Ala | 142 ± 49 | 260 ± 93 | 314 ± 85 |
| Glu162Ala | 146 ± 76 | No adhesion | No adhesion |
| Asp175Ala | No adhesion | No adhesion | No adhesion |
| Lys189Ala | 142 ± 48 | No adhesion | No adhesion |
Units for all values are μm/s.