Table 2. P 50 and n 50 values for HbF... | American Society of Hematology

Table 2.

P₅₀ and n₅₀ values for HbF treated with phthalide and 2,3-BPG under various treatment conditions

	No phthalide		Phthalide
	No phthalide		0.6 mM		1.2 mM		4.0 mM
	P₅₀	n₅₀	P₅₀	n₅₀	P₅₀	n₅₀	P₅₀	n₅₀
z-Butylidenephthalide
No 2,3-BPG	14.60	2.59	15.87	2.62	16.68	2.62	17.06	2.56
2,3-BPG
0.60 mM	14.91	2.59	16.11	2.65	16.35	2.7	17.86	2.56
1.2 mM	15.12	2.58	16.42	2.66	16.37	2.68	18.11	2.52
2.5 mM	15.92	2.59	16.62	2.66	17.4	2.71	18.63	2.52
4.0 mM	16.56	2.59	17.37	2.63	17.29	2.68	19.54	2.54
z-Ligustilide
No 2,3-BPG	14.60	2.59	15.98	2.54	16.16	2.54	16.69	2.51
2,3-BPG
0.60 mM	14.91	2.59	16.03	2.64	16.34	2.7	16.79	2.66
1.2 mM	15.12	2.58	16.48	2.65	16.58	2.7	16.84	2.67
2.5 mM	15.92	2.59	17.01	2.67	17.03	2.68	17.93	2.69
4.0 mM	16.56	2.59	17.39	2.64	18.09	2.71	18.74	2.7

	No phthalide		Phthalide
	No phthalide		0.6 mM		1.2 mM		4.0 mM
	P₅₀	n₅₀	P₅₀	n₅₀	P₅₀	n₅₀	P₅₀	n₅₀
z-Butylidenephthalide
No 2,3-BPG	14.60	2.59	15.87	2.62	16.68	2.62	17.06	2.56
2,3-BPG
0.60 mM	14.91	2.59	16.11	2.65	16.35	2.7	17.86	2.56
1.2 mM	15.12	2.58	16.42	2.66	16.37	2.68	18.11	2.52
2.5 mM	15.92	2.59	16.62	2.66	17.4	2.71	18.63	2.52
4.0 mM	16.56	2.59	17.37	2.63	17.29	2.68	19.54	2.54
z-Ligustilide
No 2,3-BPG	14.60	2.59	15.98	2.54	16.16	2.54	16.69	2.51
2,3-BPG
0.60 mM	14.91	2.59	16.03	2.64	16.34	2.7	16.79	2.66
1.2 mM	15.12	2.58	16.48	2.65	16.58	2.7	16.84	2.67
2.5 mM	15.92	2.59	17.01	2.67	17.03	2.68	17.93	2.69
4.0 mM	16.56	2.59	17.39	2.64	18.09	2.71	18.74	2.7

P₅₀ units are mm Hg.