Table 1. Comparison of P 50 values of... | American Society of Hematology

Table 1.

Comparison of P₅₀ values of HbF cotreated with 2,3-BPG and phthalides vs that of HbA treated solely with 2,3-BPG

Effector	HbA	HbF	ΔP₅₀, mm Hg
0.6 mM 2,3-BPG	16.24	15.05	−1.19
0.6 mM 2,3-BPG + 0.6 mM z-butylidenephthalide	–	16.30	0.06
4 mM 2,3-BPG	18.83	16.56	−2.27
4 mM 2,3-BPG + 2.5 mM z-butylidenephthalide	–	18.63	0.20
4 mM 2,3-BPG + 4 mM z-butylidenephthalide	–	19.54	0.71
4 mM 2,3-BPG + 4 mM z-ligustilide	–	18.74	0.09

Effector	HbA	HbF	ΔP₅₀, mm Hg
0.6 mM 2,3-BPG	16.24	15.05	−1.19
0.6 mM 2,3-BPG + 0.6 mM z-butylidenephthalide	–	16.30	0.06
4 mM 2,3-BPG	18.83	16.56	−2.27
4 mM 2,3-BPG + 2.5 mM z-butylidenephthalide	–	18.63	0.20
4 mM 2,3-BPG + 4 mM z-butylidenephthalide	–	19.54	0.71
4 mM 2,3-BPG + 4 mM z-ligustilide	–	18.74	0.09

▵P₅₀ = (P₅₀ of HbF cotreated with 2,3-BPG and chosen phthalide) – (P₅₀ of HbA treated solely with 2,3-BPG at the same level).