Table 3.

Multivariable analysis of associations of baseline characteristics and clinical outcomes

CharacteristicNo.OSDFS
Adjusted HR*95% CIP*Adjusted HR*95% CIP*
Sex        
 Male 65 Ref  .005 Ref  .008 
 Female 45 0.37 0.18-0.74  0.41 0.21-0.79  
Donor type        
 MRD 51 Ref  <.001 Ref  <.001 
 MUD 10/10 44 1.43 0.70-2.95  2.38 1.21-4.68  
 mMUD 15 8.32 3.47-19.93  6.30 2.69-14.74  
MF        
 Primary 58 Ref  .094 Ref  .024 
 Secondary 52 0.56 0.29-1.10  0.48 0.26-0.91  
Cytogenetics        
 Favorable 67 Ref  .001 Ref  .008 
 Unfavorable 24 2.31 1.05-5.07  1.39 0.66-2.94  
 VHR 15 4.19 1.93-9.13  3.14 1.53-6.47  
MIPSS70+ v2.0 classification†        
 Intermediate risk 11 0.29 0.04-2.26 <.001 0.24 0.03-1.91 <.001 
 High risk 47 Ref   Ref   
 VHR 35 5.05 2.39-10.70  3.87 1.90-7.88  
CharacteristicNo.OSDFS
Adjusted HR*95% CIP*Adjusted HR*95% CIP*
Sex        
 Male 65 Ref  .005 Ref  .008 
 Female 45 0.37 0.18-0.74  0.41 0.21-0.79  
Donor type        
 MRD 51 Ref  <.001 Ref  <.001 
 MUD 10/10 44 1.43 0.70-2.95  2.38 1.21-4.68  
 mMUD 15 8.32 3.47-19.93  6.30 2.69-14.74  
MF        
 Primary 58 Ref  .094 Ref  .024 
 Secondary 52 0.56 0.29-1.10  0.48 0.26-0.91  
Cytogenetics        
 Favorable 67 Ref  .001 Ref  .008 
 Unfavorable 24 2.31 1.05-5.07  1.39 0.66-2.94  
 VHR 15 4.19 1.93-9.13  3.14 1.53-6.47  
MIPSS70+ v2.0 classification†        
 Intermediate risk 11 0.29 0.04-2.26 <.001 0.24 0.03-1.91 <.001 
 High risk 47 Ref   Ref   
 VHR 35 5.05 2.39-10.70  3.87 1.90-7.88  
*

Based on the multivariable Cox regression model adjusting for sex, donor type, and cytogenetics.

†

Based on the multivariable Cox regression model adjusting for sex and donor type, but not for cytogenetics.

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