Analysis of the breeding of single- and double-deficient mice
| Breeding pair . | Expected % of Plg genotypes . | Observed no. (%) of Plg genotypes . | ||||||
|---|---|---|---|---|---|---|---|---|
| Female . | Male . | Offspring, n . | WT . | Plg+/− . | Plg−/− . | WT . | Plg+/− . | Plg−/− . |
| Plg+/− | Plg+/− | 226 | 25 | 50 | 25 | 49 (22) | 116 (51) | 61 (27) |
| Plg+/− | Plg−/− | 89 | — | 50 | 50 | — | 49 (55) | 40 (45) |
| F8−/−/Plg+/− | F8−/−/Plg+/− | 105 | 25 | 50 | 25 | 26 (25) | 51 (49) | 28 (27) |
| F8−/−/Plg+/− | F8−/−/Plg−/− | 65 | — | 50 | 50 | — | 33 (51) | 32 (49) |
| Breeding pair . | Expected % of Plg genotypes . | Observed no. (%) of Plg genotypes . | ||||||
|---|---|---|---|---|---|---|---|---|
| Female . | Male . | Offspring, n . | WT . | Plg+/− . | Plg−/− . | WT . | Plg+/− . | Plg−/− . |
| Plg+/− | Plg+/− | 226 | 25 | 50 | 25 | 49 (22) | 116 (51) | 61 (27) |
| Plg+/− | Plg−/− | 89 | — | 50 | 50 | — | 49 (55) | 40 (45) |
| F8−/−/Plg+/− | F8−/−/Plg+/− | 105 | 25 | 50 | 25 | 26 (25) | 51 (49) | 28 (27) |
| F8−/−/Plg+/− | F8−/−/Plg−/− | 65 | — | 50 | 50 | — | 33 (51) | 32 (49) |
The number of offspring observed at weaning from the different types of breeding pairs can be seen, as well as the expected and observed ratio of obtained mice with the respective genotypes.