Table 1.

Clinical characteristics and p16 status of study group

ParameterNumber (percentage)
Total no. 45 
Sex  
 Female 14  (31)  
 Male 31  (69) 
Age  
 <1 y 1  (2)  
 1 y-10 y 30  (67) 
 >10 y 14  (31)  
Immunophenotype  
 T-ALL 13  (29)  
 B-lineage ALL 32  (71)  
WCC at diagnosis  
 <50 000 × 106/L 26  (58) 
 ≥50 000 × 106/L 19  (42)  
P16genotype  
 G/G 28  (62)  
 D/D 11  (25) 
 G/D 6  (13) 
ParameterNumber (percentage)
Total no. 45 
Sex  
 Female 14  (31)  
 Male 31  (69) 
Age  
 <1 y 1  (2)  
 1 y-10 y 30  (67) 
 >10 y 14  (31)  
Immunophenotype  
 T-ALL 13  (29)  
 B-lineage ALL 32  (71)  
WCC at diagnosis  
 <50 000 × 106/L 26  (58) 
 ≥50 000 × 106/L 19  (42)  
P16genotype  
 G/G 28  (62)  
 D/D 11  (25) 
 G/D 6  (13) 

T-ALL indicates T-lineage acute lymphoblastic leukemia: WCC, white cell count; G/G, germline p16; D/D p16deletion; G/D, hemizygous p16.

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