Table 4.

Bone marrow morphology

UPNCellularityGranulopoiesisPMN (%)Post-mitotic:mitotic ratioM:E ratio
PretherapyOn therapyPretherapyOn therapyPretherapyOn therapyPretherapyOn therapyPretherapyOn therapy
21 normal hypercellular arrest at myelocytes normal 28 0.6:1 1:1 0.8:1 6:1 
22 — hypercellular — normal — 23 — 0.7:1 — 6:1 
23 hypercellular hypercellular normal normal 44 — 7:1 3.6:1 5:1 9:1 
24 hypercellular hypercellular normal normal 13 2.4:1 1:1 5:1 8:1 
25 hypercellular hypercellular arrest at bands normal — 35 — 1.8:1 — 6:1 
26 normal hypercellular arrest at metamyelocytes normal 23 1.9:1 1.6:1 1.5:1 4:1 
27 hypercellular normal normal normal 11 1.3:1 5.5:1 1.7:1 5.2:1 
34 hypercellular hypercellular normal normal 32 28 3:1 0.8:1 6:1 8:1 
35 hypercellular hypercellular normal normal — — — — 10:1 — 
UPNCellularityGranulopoiesisPMN (%)Post-mitotic:mitotic ratioM:E ratio
PretherapyOn therapyPretherapyOn therapyPretherapyOn therapyPretherapyOn therapyPretherapyOn therapy
21 normal hypercellular arrest at myelocytes normal 28 0.6:1 1:1 0.8:1 6:1 
22 — hypercellular — normal — 23 — 0.7:1 — 6:1 
23 hypercellular hypercellular normal normal 44 — 7:1 3.6:1 5:1 9:1 
24 hypercellular hypercellular normal normal 13 2.4:1 1:1 5:1 8:1 
25 hypercellular hypercellular arrest at bands normal — 35 — 1.8:1 — 6:1 
26 normal hypercellular arrest at metamyelocytes normal 23 1.9:1 1.6:1 1.5:1 4:1 
27 hypercellular normal normal normal 11 1.3:1 5.5:1 1.7:1 5.2:1 
34 hypercellular hypercellular normal normal 32 28 3:1 0.8:1 6:1 8:1 
35 hypercellular hypercellular normal normal — — — — 10:1 — 

Bone marrow morphology was assessed on Wright-Giemsa stain. PMN indicates the percentage of segmented neutrophil identified on a differential count of total nucleated cells. The postmitotic:mitotic ratio equals the neutrophils + bands + metamyelocytes/myelocytes + promyelocytes + blasts.

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