Table 2.

Neutrophil response

UPNPretherapy ANC,
mean
Steady-state
ANC, mean
Response
21 0.4 1.8 CR 
22 N/A 2.7 N/A  
23 1.3 5.13 N/A 
24 0.27 1.44 CR  
25 0.68 2.20 CR 
26 0.13 1.83 CR  
27 0.27 0.89 PR 
28 0.64 2.15 CR  
31 0.34 3.11 N/A 
32 0.58 1.82 CR  
33 0.30 2.22 CR 
34 0.14 3.0 CR  
35 0.44 3.36 CR 
 mean = 0.46 mean = 2.43 P < .01 
UPNPretherapy ANC,
mean
Steady-state
ANC, mean
Response
21 0.4 1.8 CR 
22 N/A 2.7 N/A  
23 1.3 5.13 N/A 
24 0.27 1.44 CR  
25 0.68 2.20 CR 
26 0.13 1.83 CR  
27 0.27 0.89 PR 
28 0.64 2.15 CR  
31 0.34 3.11 N/A 
32 0.58 1.82 CR  
33 0.30 2.22 CR 
34 0.14 3.0 CR  
35 0.44 3.36 CR 
 mean = 0.46 mean = 2.43 P < .01 

Pretherapy ANC indicates the mean of all available ANCs for each patient prior to initiation of cytokine therapy. The steady-state ANC indicates the mean of all available ANCs for each patient during maintenance phase. CR is the mean ANC > 1.0 × 109 cells/L, and PR is the mean ANC between 0.8 and 1.0 × 109 cells/L. The P value was obtained by the t test for paired data.

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