Skin graft results after transplant on BALB/c hosts
Group . | Peripheral blood chimerism (%) . | Graft time after BMT (wk) . | Skin graft B6.SJL . | Skin graft CBA/J . |
---|---|---|---|---|
Normal BALB/c mice | 0 | NA | — | — |
0 | NA | — | — | |
0 | NA | — | — | |
0 | NA | — | — | |
0 | NA | — | — | |
Standard protocol | 46.1 | 8 | +(>7 wk) | — |
(1.6 mg anti-CD40 | 37.9 | 8 | +(>7 wk) | — |
ligand antibody) | 40.9 | 8 | +(>7 wk) | — |
33.3 | 9 | +(>7 wk) | — | |
35.6 | 9 | +(>7 wk) | — | |
26.7 | 39 | +(>6 wk) | — | |
30.3 | 39 | +(>6 wk) | — | |
31.3 | 39 | +(>6 wk) | — | |
27.6 | 43 | +(>31 wk) | — | |
31.5 | 43 | +(23 wk)* | — | |
Standard protocol or | 0.1 | 8 | — | — |
variants of standard | 0.03 | 8 | — | — |
protocol | 0.33 | 39 | — | — |
0 | 39 | — | — | |
0 | 43 | — | — | |
0 | 43 | — | — |
Group . | Peripheral blood chimerism (%) . | Graft time after BMT (wk) . | Skin graft B6.SJL . | Skin graft CBA/J . |
---|---|---|---|---|
Normal BALB/c mice | 0 | NA | — | — |
0 | NA | — | — | |
0 | NA | — | — | |
0 | NA | — | — | |
0 | NA | — | — | |
Standard protocol | 46.1 | 8 | +(>7 wk) | — |
(1.6 mg anti-CD40 | 37.9 | 8 | +(>7 wk) | — |
ligand antibody) | 40.9 | 8 | +(>7 wk) | — |
33.3 | 9 | +(>7 wk) | — | |
35.6 | 9 | +(>7 wk) | — | |
26.7 | 39 | +(>6 wk) | — | |
30.3 | 39 | +(>6 wk) | — | |
31.3 | 39 | +(>6 wk) | — | |
27.6 | 43 | +(>31 wk) | — | |
31.5 | 43 | +(23 wk)* | — | |
Standard protocol or | 0.1 | 8 | — | — |
variants of standard | 0.03 | 8 | — | — |
protocol | 0.33 | 39 | — | — |
0 | 39 | — | — | |
0 | 43 | — | — | |
0 | 43 | — | — |
Grafts transplanted on the dorsal surface with B6.SJL on the left and CBA/J on the right side.
BMT indicates bone marrow transplant; NA, not applicable; —, rejection (rejection was completed within 10-12 days of graft application); +, accepted graft (number of weeks in parentheses represents duration of graft after graft application).
This mouse died at 56 weeks after marrow graft, 23 weeks after skin graft; cause unknown.