Table 1.

IGVL gene usage of patients with pLCDD and pAL amyloidosis

This table shows the most informative proteomic data obtained using LC-MS/MS analysis of peptides. The best MS/MS count is indicated for each peptide derived from the light chain variable region. Overall, we found immunoglobulin peptides from the light chain variable region in 75.7% of patients. Remarkably, we observed that IGKV1-8 was overrepresented in pLCDD, especially the diffuse cystic form.

B, involvement of the main bronchi and bronchioles; CT, computed tomography; ILD, diffuse interstitial lung disease without cysts; K, diffuse cystic lung disorder; N, isolated pulmonary nodule; NI, not identified; U, unique peptide.

*Peptides identified using a “match between run” data analysis based on ion intensities.

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