Table 1.

Patient characteristics

No. of patients841
Median age at diagnosis, y (range) 57.2 (30-91) 
Sex  
 Male 503 (60%) 
 Female 338 (40%) 
Rai stage  
 0-1 657 (78%) 
 2 126 (15%) 
 3-4 58 (7%) 
Median time from diagnosis to Sc, y 
Median TFS, y 
No. of treated patients 533 (63%) 
No. of patients with IGHV status 830 (98%) 
 IGHVUM 376 (45%) 
 IGHVMU 454 (55%) 
No. of patients with ZAP-70 expression 838 (99%) 
 ZAP-70 positive 307 (37%) 
 ZAP-70 negative 531 (63%) 
No. of patients with fluorescence in situ hybridization data 656 (78%) 
 Del(17p) 64 (10%) 
 Del(11q) 78 (12%) 
 Trisomy 12 103 (16%) 
 Del(13q) 263 (40%) 
 Normal karyotype 146 (22%) 
No. of patients841
Median age at diagnosis, y (range) 57.2 (30-91) 
Sex  
 Male 503 (60%) 
 Female 338 (40%) 
Rai stage  
 0-1 657 (78%) 
 2 126 (15%) 
 3-4 58 (7%) 
Median time from diagnosis to Sc, y 
Median TFS, y 
No. of treated patients 533 (63%) 
No. of patients with IGHV status 830 (98%) 
 IGHVUM 376 (45%) 
 IGHVMU 454 (55%) 
No. of patients with ZAP-70 expression 838 (99%) 
 ZAP-70 positive 307 (37%) 
 ZAP-70 negative 531 (63%) 
No. of patients with fluorescence in situ hybridization data 656 (78%) 
 Del(17p) 64 (10%) 
 Del(11q) 78 (12%) 
 Trisomy 12 103 (16%) 
 Del(13q) 263 (40%) 
 Normal karyotype 146 (22%) 

Sc, sample collection.

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