Five-year outcome at joint level
| Variable . | Severe hemophilia on prophylaxis . | Moderate hemophilia treated on demand . | Overall* . | P† . |
|---|---|---|---|---|
| N | 55 | 32 | 92 | |
| Treatment, n | ||||
| Prophylaxis | 55 | 0 | 58 | |
| Bleeding | ||||
| 5-y bleeding | 18/55 (33) | 12/32 (38) | 33/92 (36) | .65 |
| No. of joint bleeds | 0 (0-1) | 0 (0-1) | 0 (0-1) | .72 |
| Progression of arthropathy | ||||
| Progression of arthropathy | 4/55 (7) | 3/32 (9) | 8/92 (9) | .53 |
| Pettersson score at follow-up | 0 (0-0) | 0 (0-0) | 0 (0-0) | .80 |
| Variable . | Severe hemophilia on prophylaxis . | Moderate hemophilia treated on demand . | Overall* . | P† . |
|---|---|---|---|---|
| N | 55 | 32 | 92 | |
| Treatment, n | ||||
| Prophylaxis | 55 | 0 | 58 | |
| Bleeding | ||||
| 5-y bleeding | 18/55 (33) | 12/32 (38) | 33/92 (36) | .65 |
| No. of joint bleeds | 0 (0-1) | 0 (0-1) | 0 (0-1) | .72 |
| Progression of arthropathy | ||||
| Progression of arthropathy | 4/55 (7) | 3/32 (9) | 8/92 (9) | .53 |
| Pettersson score at follow-up | 0 (0-0) | 0 (0-0) | 0 (0-0) | .80 |
Data are presented as the median (IQR) or n/N (%) unless otherwise stated. Four ankles with a baseline Pettersson score ≥4 were excluded.
Including 2 joints of 1 patient with severe hemophilia treated on demand, and 3 joints of 1 patient with moderate hemophilia on prophylaxis.
P value for comparison of patients with severe hemophilia on prophylaxis/patients with moderate hemophilia treated on demand, adjusted for clustering of joints within patients.