Conversion table
| Model . | cTnT, μg/L . | cTnI, μg/L . | Hs-cTnT, ng/L . | NT-proBNP, ng/L . | BNP, ng/L . |
|---|---|---|---|---|---|
| AL amyloidosis | |||||
| Mayo 2004 model* | ≥0.035 | ≥0.1 | ≥50†‡ | ≥332 | 8121 |
| Euro 2015 modification of Mayo 2004 model§ | ≥0.035 | ≥0.1† | ≥50†‡ | ≥332 | 8121 |
| >8500 | >70021 | ||||
| Mayo 2012 model‖ | ≥0.025 | ND | ≥41‡ | ≥1800 | ≥400¶ |
| Round >40 | |||||
| Mayo ASCT troponin risk marker# | ≥0.06 | ND | ≥73‡ | NA | NA |
| Round ≥75 | |||||
| ATTR | |||||
| Mayo ATTRwt | >0.05 | ND | >65‡ | 3000 | ND |
| NAC ATTR** | NA | NA | NA | 3000 | NA |
| Model . | cTnT, μg/L . | cTnI, μg/L . | Hs-cTnT, ng/L . | NT-proBNP, ng/L . | BNP, ng/L . |
|---|---|---|---|---|---|
| AL amyloidosis | |||||
| Mayo 2004 model* | ≥0.035 | ≥0.1 | ≥50†‡ | ≥332 | 8121 |
| Euro 2015 modification of Mayo 2004 model§ | ≥0.035 | ≥0.1† | ≥50†‡ | ≥332 | 8121 |
| >8500 | >70021 | ||||
| Mayo 2012 model‖ | ≥0.025 | ND | ≥41‡ | ≥1800 | ≥400¶ |
| Round >40 | |||||
| Mayo ASCT troponin risk marker# | ≥0.06 | ND | ≥73‡ | NA | NA |
| Round ≥75 | |||||
| ATTR | |||||
| Mayo ATTRwt | >0.05 | ND | >65‡ | 3000 | ND |
| NAC ATTR** | NA | NA | NA | 3000 | NA |
NA, not applicable; ND, no data.
Original 3 stage model using cTnT and NT-proBNP cut points as listed. cTnI also tested in the same paper.
In prior study, hs-cTnT 54 ng/L found to be comparable to cTnT cut point of 0.035 μg/L, but reanalysis using quartic formula yielded a value of 50 ng/L.
Extrapolated numbers are based on quartic formula applied to a data set of 224 newly diagnosed AL amyloidosis patients.10
Original 3 stage model using cTnT and NT-proBNP cut points as listed, but separate stage III into IIIa and IIIb based on whether or not NT-proBNP is >8500 ng/L.
Four stage model using cTnT and NT-proBNP cut points as listed along with difference of involved to uninvolved free light chain ≥18 mg/dL.
In original study, BNP threshold was found to be comparable NT-proBNP threshold.
Simple binary troponin T threshold predicting for transplant-related mortality 25% vs 4%.
eGFR threshold of <45 mL/min/1.73 m2 is used in addition to the NT-proBNP.