Patient and disease characteristics and transplantation evolution
| Characteristics . | Data . |
|---|---|
| Patients | |
| Age at transplantation, median (IQR), y | 43 (33.8-61.5) |
| Weight at transplantation, median (IQR), kg | 62 (59.3-80) |
| Males | 14 (58) |
| Disease | |
| Acute lymphoid leukemia | 9 (38) |
| Myeloproliferative disorders | 6 (25) |
| Acute myeloid leukemia | 5 (21) |
| Lymphoma | 3 (12) |
| Aplastic anemia | 1 (4) |
| Donor type | |
| Matched family donor | 7 (29) |
| Mismatched family donor (haploidentical) | 7 (29) |
| Matched unrelated donor | 6 (25) |
| Mismatched unrelated donor | 4 (17) |
| Source of stem cells and conditioning regimen | |
| Peripheral blood stem cells/bone marrow | 15/9 (62/38) |
| MAC/RIC | 17/7 (71/29) |
| Main outcome posttransplantation | |
| Acute GvHD | |
| 100-d CumI, % (95% CI) | 50 (29-71) |
| Grade II/III/IV, n | 11/1/0 |
| Chronic GvHD | |
| 1-y CumI, % (95% CI) | 55 (29-71) |
| Mild/moderate/severe, n | 5/6/1 |
| Relapse, n | 4 |
| 1-y CumI, % (95% CI) | 13 (0-27) |
| Deaths, n* | 6 |
| Relapse | 2 |
| Infections | 2 |
| Acute respiratory distress syndrome | 2 |
| Characteristics . | Data . |
|---|---|
| Patients | |
| Age at transplantation, median (IQR), y | 43 (33.8-61.5) |
| Weight at transplantation, median (IQR), kg | 62 (59.3-80) |
| Males | 14 (58) |
| Disease | |
| Acute lymphoid leukemia | 9 (38) |
| Myeloproliferative disorders | 6 (25) |
| Acute myeloid leukemia | 5 (21) |
| Lymphoma | 3 (12) |
| Aplastic anemia | 1 (4) |
| Donor type | |
| Matched family donor | 7 (29) |
| Mismatched family donor (haploidentical) | 7 (29) |
| Matched unrelated donor | 6 (25) |
| Mismatched unrelated donor | 4 (17) |
| Source of stem cells and conditioning regimen | |
| Peripheral blood stem cells/bone marrow | 15/9 (62/38) |
| MAC/RIC | 17/7 (71/29) |
| Main outcome posttransplantation | |
| Acute GvHD | |
| 100-d CumI, % (95% CI) | 50 (29-71) |
| Grade II/III/IV, n | 11/1/0 |
| Chronic GvHD | |
| 1-y CumI, % (95% CI) | 55 (29-71) |
| Mild/moderate/severe, n | 5/6/1 |
| Relapse, n | 4 |
| 1-y CumI, % (95% CI) | 13 (0-27) |
| Deaths, n* | 6 |
| Relapse | 2 |
| Infections | 2 |
| Acute respiratory distress syndrome | 2 |
N = 24 patients. Unless otherwise indicated, data are n (%).
MAC, myeloablative conditioning; RIC, reduced-intensity conditioning
Deaths occurred at days +40, +59, +86, +188, +210, and +223 after inclusion.