Indication for IV iron therapy
| Condition . | Reason . |
|---|---|
| Oral iron intolerance | Persistent gastrointestinal adverse effects |
| Oral iron refractoriness | Defective absorption: gastrectomy, duodenal bypass, bariatric surgery |
| Intestinal disorders (selected cases): IBD, atrophic gastritis, Helicobacter pylori infection, gluten enteropathy | |
| Genetic forms (IRIDA) | |
| No Hb improvement after 4 wk of oral therapy | |
| Severe anemia (Hb <7-8 g/dL) | Need for rapid Hb improvement |
| Second and third trimesters of pregnancy | Need for rapid Hb increase; often intolerance to oral preparations |
| ESA treatment | More effective than oral iron in CKD |
| Chronic blood loss difficult to manage with oral iron | Heavy uterine bleeding |
| Hereditary disorders of hemostasis | |
| Other | Postoperative anemia of major surgery |
| Chronic systolic heart failure |
| Condition . | Reason . |
|---|---|
| Oral iron intolerance | Persistent gastrointestinal adverse effects |
| Oral iron refractoriness | Defective absorption: gastrectomy, duodenal bypass, bariatric surgery |
| Intestinal disorders (selected cases): IBD, atrophic gastritis, Helicobacter pylori infection, gluten enteropathy | |
| Genetic forms (IRIDA) | |
| No Hb improvement after 4 wk of oral therapy | |
| Severe anemia (Hb <7-8 g/dL) | Need for rapid Hb improvement |
| Second and third trimesters of pregnancy | Need for rapid Hb increase; often intolerance to oral preparations |
| ESA treatment | More effective than oral iron in CKD |
| Chronic blood loss difficult to manage with oral iron | Heavy uterine bleeding |
| Hereditary disorders of hemostasis | |
| Other | Postoperative anemia of major surgery |
| Chronic systolic heart failure |
IBD, inflammatory bowel disease.