Initial slopes of the activity-over-time curves
| FXIII-A variant . | Slope 3-10 min, ΔOD/min . | P . | Slope 3-20 min, ΔOD/min . | P . |
|---|---|---|---|---|
| Wild-type | 0.0403 ± 0.0116 | — | 0.0443 ± 0.0051 | — |
| Arg100Gln | 0.0291 ± 0.0239 | n.s. | 0.0207 ± 0.0049 | <.001 |
| Arg100Leu | 0.0249 ± 0.0224 | n.s. | 0.0213 ± 0.0034 | <.001 |
| Glu111Leu | 0.0585 ± 0.0124 | .067 | 0.0457 ± 0.0073 | n.s. |
| Asn112Val | 0.0343 ± 0.0418 | n.s. | 0.0427 ± 0.0081 | n.s. |
| FXIII-A variant . | Slope 3-10 min, ΔOD/min . | P . | Slope 3-20 min, ΔOD/min . | P . |
|---|---|---|---|---|
| Wild-type | 0.0403 ± 0.0116 | — | 0.0443 ± 0.0051 | — |
| Arg100Gln | 0.0291 ± 0.0239 | n.s. | 0.0207 ± 0.0049 | <.001 |
| Arg100Leu | 0.0249 ± 0.0224 | n.s. | 0.0213 ± 0.0034 | <.001 |
| Glu111Leu | 0.0585 ± 0.0124 | .067 | 0.0457 ± 0.0073 | n.s. |
| Asn112Val | 0.0343 ± 0.0418 | n.s. | 0.0427 ± 0.0081 | n.s. |
Data are presented as mean ± standard deviation. The P value describes the comparison with the wild-type tested by using the Student t test.
ΔOD/min, change of optical density per minute; n.s., not significant.