Patient characteristics of 3 autopsy cases
Patient . | Age, y . | Primary disease . | Donor type . | Stem cell source . | Conditioning . | Hepatitis infections . | Acute GVHD . | Onset of liver GVHD, d . | Onset of lung cGVHD, d . | Other cGVHD . | Death, d . | Cause of death . |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 44 | AML | MRD | PB | Cy/TBI | HBsAg(+) | None | +94 | None | Skin | +887 | Liver failure |
2 | 66 | CMMoL | MRD | PB | Flu/Bu | None | Grade I | +123 | +186 | Skin | +372 | BO |
3 | 58 | FL | Haplo | PB | Flu/Mel/TBI | None | None | None | +444 | None | +618 | Multiple infections |
Patient . | Age, y . | Primary disease . | Donor type . | Stem cell source . | Conditioning . | Hepatitis infections . | Acute GVHD . | Onset of liver GVHD, d . | Onset of lung cGVHD, d . | Other cGVHD . | Death, d . | Cause of death . |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 44 | AML | MRD | PB | Cy/TBI | HBsAg(+) | None | +94 | None | Skin | +887 | Liver failure |
2 | 66 | CMMoL | MRD | PB | Flu/Bu | None | Grade I | +123 | +186 | Skin | +372 | BO |
3 | 58 | FL | Haplo | PB | Flu/Mel/TBI | None | None | None | +444 | None | +618 | Multiple infections |
AML, acute myeloid leukemia; Bu, busulfan; CMMoL, chronic myelomonocytic leukemia; Cy, cyclophosphamide; FL, follicular lymphoma; Flu, fludarabine; Haplo, haploidentical donor; Mel, melphalan; HBsAg, hepatitis B surface antigen; MRD, matched related donor; PB, peripheral blood stem cells; TBI, total body irradiation.