Table 4.

Patient characteristics of 3 autopsy cases

PatientAge, yPrimary diseaseDonor typeStem cell sourceConditioningHepatitis infectionsAcute GVHDOnset of liver GVHD, dOnset of lung cGVHD, dOther cGVHDDeath, dCause of death
44 AML MRD PB Cy/TBI HBsAg(+) None +94 None Skin +887 Liver failure 
66 CMMoL MRD PB Flu/Bu None Grade I +123 +186 Skin +372 BO 
58 FL Haplo PB Flu/Mel/TBI None None None +444 None +618 Multiple infections 
PatientAge, yPrimary diseaseDonor typeStem cell sourceConditioningHepatitis infectionsAcute GVHDOnset of liver GVHD, dOnset of lung cGVHD, dOther cGVHDDeath, dCause of death
44 AML MRD PB Cy/TBI HBsAg(+) None +94 None Skin +887 Liver failure 
66 CMMoL MRD PB Flu/Bu None Grade I +123 +186 Skin +372 BO 
58 FL Haplo PB Flu/Mel/TBI None None None +444 None +618 Multiple infections 

AML, acute myeloid leukemia; Bu, busulfan; CMMoL, chronic myelomonocytic leukemia; Cy, cyclophosphamide; FL, follicular lymphoma; Flu, fludarabine; Haplo, haploidentical donor; Mel, melphalan; HBsAg, hepatitis B surface antigen; MRD, matched related donor; PB, peripheral blood stem cells; TBI, total body irradiation.

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