Clinical characteristics of the 10 analyzed patients
| UPN . | 107 . | 202 . | 316 . | 318 . | 337 . | 514 . | 590 . | 660 . | 685 . | 735 . |
|---|---|---|---|---|---|---|---|---|---|---|
| Sex | F | F | M | M | M | M | F | M | F | M |
| Age at first disease, y | 0.3 | 5.7 | 1.0 | 5.3 | 2.8 | 2.5 | 7.3 | 5.1 | 5.7 | 10.2 |
| Immunophenotype | cALL | cALL | cALL | cALL | cALL | cALL | cALL | cort. T | pro-T | pB-ALL |
| Age at relapse, y | n/a | 7.5 | 3.3 | 7.7 | 5.9 | 5.0 | 10.7 | 6.4 | 6.8 | 12.3 |
| Time to relapse, y | n/a | 1.8 | 2.3 | 2.4 | 3.1 | 2.5 | 3.4 | 1.3 | 1.1 | 2.1 |
| Age at SCT, y | 0.8 | 8.1 | 3.9 | 8.0 | 6.3 | 5.5 | 11.2 | 6.7 | 7.0 | 12.8 |
| MRD before SCT | <1 × 10−4 | <1 × 10−3-1 × 10−4 | 1 × 10−6 | 1 × 10−4 | <1 × 10−4 | <1 × 10−4 | <1 × 10−5 | <1 × 10−4 | 1 × 10−3-1 × 10−4 | <1 × 10−4 |
| Time to relapse after SCT, y | 0.3 | 0.7 | 0.4 | 1.7 | 1.2 | 0.3 | 1.2 | 0.6 | 0.2 | 0.2 |
| Survival status | Alive | Dead | Dead | Alive | Dead | Dead | Dead | Dead | Dead | Dead |
| UPN . | 107 . | 202 . | 316 . | 318 . | 337 . | 514 . | 590 . | 660 . | 685 . | 735 . |
|---|---|---|---|---|---|---|---|---|---|---|
| Sex | F | F | M | M | M | M | F | M | F | M |
| Age at first disease, y | 0.3 | 5.7 | 1.0 | 5.3 | 2.8 | 2.5 | 7.3 | 5.1 | 5.7 | 10.2 |
| Immunophenotype | cALL | cALL | cALL | cALL | cALL | cALL | cALL | cort. T | pro-T | pB-ALL |
| Age at relapse, y | n/a | 7.5 | 3.3 | 7.7 | 5.9 | 5.0 | 10.7 | 6.4 | 6.8 | 12.3 |
| Time to relapse, y | n/a | 1.8 | 2.3 | 2.4 | 3.1 | 2.5 | 3.4 | 1.3 | 1.1 | 2.1 |
| Age at SCT, y | 0.8 | 8.1 | 3.9 | 8.0 | 6.3 | 5.5 | 11.2 | 6.7 | 7.0 | 12.8 |
| MRD before SCT | <1 × 10−4 | <1 × 10−3-1 × 10−4 | 1 × 10−6 | 1 × 10−4 | <1 × 10−4 | <1 × 10−4 | <1 × 10−5 | <1 × 10−4 | 1 × 10−3-1 × 10−4 | <1 × 10−4 |
| Time to relapse after SCT, y | 0.3 | 0.7 | 0.4 | 1.7 | 1.2 | 0.3 | 1.2 | 0.6 | 0.2 | 0.2 |
| Survival status | Alive | Dead | Dead | Alive | Dead | Dead | Dead | Dead | Dead | Dead |
cort., cortical; F, female; M, male; MRD, minimal residual disease; SCT, stem cell transplantation; UPN, unique patient identifier.