Table 3

Analysis of clonotypes present in the colon and corresponding clonotype frequencies in the input splenic population

Vβ familyClonotype nameNo. of sequences (colon)% of sequences (colon)No. of sequences (spleen)% of sequences (spleen)
Vβ2 sAa.1 87 70.7 5 0.08 
 aGPn.43 15 12.2 0 < 0.02 
 sGTFs.431 14 11.4 < 0.02 
 sAHREs.2261 2.4 < 0.02 
 aGVn.343 1.6 < 0.02 
 sANRESGNTl.22611311 0.81 < 0.02 
 aGDt.42 0.81 10 0.16 
Vβ8.3 dLa.3 37 50.7 0 < 0.3 
 dDWVs.211 14 19.2 < 0.3 
 dGGe.44 10.9 < 0.3 
 sATIs.431 6.8 < 0.3 
 sDRGLq.2424 4.1 < 0.3 
 sSRGQDt.623 22 2.7 0.62 
 dGDRGRDDe.426451 1.4 < 0.3 
 aISDRGLq.252424 1.4 < 0.3 
 sDRGIq.2422 1.4 < 0.3 
 sEGy.14 1.4 0.31 
Vβ16 lKDGn.223 62 53.0 69 0.60 
 lAGDg.341 34 29.1 507 4.4 
 lRGDq.442 13 11.1 < 0.0001 
 lGLGGq.4642 4 3.4 0 < 0.0001 
 sGQFs.321 0.86 < 0.0001 
 sFDWGe.1213 0.85 37 0.32 
 lVGRe.446 0.85 191 1.7 
 lRWGy.412 0.85 35 0.30 
Vβ familyClonotype nameNo. of sequences (colon)% of sequences (colon)No. of sequences (spleen)% of sequences (spleen)
Vβ2 sAa.1 87 70.7 5 0.08 
 aGPn.43 15 12.2 0 < 0.02 
 sGTFs.431 14 11.4 < 0.02 
 sAHREs.2261 2.4 < 0.02 
 aGVn.343 1.6 < 0.02 
 sANRESGNTl.22611311 0.81 < 0.02 
 aGDt.42 0.81 10 0.16 
Vβ8.3 dLa.3 37 50.7 0 < 0.3 
 dDWVs.211 14 19.2 < 0.3 
 dGGe.44 10.9 < 0.3 
 sATIs.431 6.8 < 0.3 
 sDRGLq.2424 4.1 < 0.3 
 sSRGQDt.623 22 2.7 0.62 
 dGDRGRDDe.426451 1.4 < 0.3 
 aISDRGLq.252424 1.4 < 0.3 
 sDRGIq.2422 1.4 < 0.3 
 sEGy.14 1.4 0.31 
Vβ16 lKDGn.223 62 53.0 69 0.60 
 lAGDg.341 34 29.1 507 4.4 
 lRGDq.442 13 11.1 < 0.0001 
 lGLGGq.4642 4 3.4 0 < 0.0001 
 sGQFs.321 0.86 < 0.0001 
 sFDWGe.1213 0.85 37 0.32 
 lVGRe.446 0.85 191 1.7 
 lRWGy.412 0.85 35 0.30 

Numbers in bold denote clonotypes present in the colon that were shared by multiple mice (as depicted in Figure 3) and the corresponding frequency of these sequences in the input splenic T-cell population and in the colon.

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