Table 1 Trends in AML allogeneic... | American Society of Hematology

Table 1

Trends in AML allogeneic transplant activity: cases registered with the CIBMTR

	1998	1999	2000	2001	2002	2003	2004	2005	2006	2007	2008
No of centers reporting to CIBMTR	162	171	189	208	220	208	222	210	212	197	184
AML patients undergoing allo-HCT, all ages
All patients	1778	1826	2045	2119	2324	2326	2621	2735	2697	2581	2557
RD	1286	1288	1359	1319	1462	1382	1444	1485	1436	1284	1223
vURD	443	474	627	697	744	822	1046	1091	1053	1085	1114
UCB	49	64	59	103	118	122	131	159	208	212	220
Adult*AML allo-HCT patients using vURD
CR1	72	88	153	186	211	273	353	422	441	467	518
≥ CR2	99	104	148	162	173	161	245	258	212	239	221
Not in remission	126	118	149	155	179	193	242	216	225	173	278
Adult*AML allo-HCT patients using UCB
CR1	3	4	9	9	14	14	16	29	43	39	47
≥ CR2	4	7	4	12	8	8	17	27	30	39	45
Not in remission	4	4	5	16	5	9	14	11	21	24	38
Graft source on all adult AML patients, %
Related donor
PB	43	54	65	74	76	83	83	87	87	88	88
BM	57	46	34	26	24	17	17%	13	13	12	12
UCB	0.5	0.3	0.6	0	0	0	0%	0.1	0	0.2	0
Unrelated donor
PB	4	13	29	39	46	60	68	69	70	71	75
BM	91	83	68	55	50	34	26	23	19	18	14
UCB	5	5	4	6	5	6	6	8	11	11	11

	1998	1999	2000	2001	2002	2003	2004	2005	2006	2007	2008
No of centers reporting to CIBMTR	162	171	189	208	220	208	222	210	212	197	184
AML patients undergoing allo-HCT, all ages
All patients	1778	1826	2045	2119	2324	2326	2621	2735	2697	2581	2557
RD	1286	1288	1359	1319	1462	1382	1444	1485	1436	1284	1223
vURD	443	474	627	697	744	822	1046	1091	1053	1085	1114
UCB	49	64	59	103	118	122	131	159	208	212	220
Adult*AML allo-HCT patients using vURD
CR1	72	88	153	186	211	273	353	422	441	467	518
≥ CR2	99	104	148	162	173	161	245	258	212	239	221
Not in remission	126	118	149	155	179	193	242	216	225	173	278
Adult*AML allo-HCT patients using UCB
CR1	3	4	9	9	14	14	16	29	43	39	47
≥ CR2	4	7	4	12	8	8	17	27	30	39	45
Not in remission	4	4	5	16	5	9	14	11	21	24	38
Graft source on all adult AML patients, %
Related donor
PB	43	54	65	74	76	83	83	87	87	88	88
BM	57	46	34	26	24	17	17%	13	13	12	12
UCB	0.5	0.3	0.6	0	0	0	0%	0.1	0	0.2	0
Unrelated donor
PB	4	13	29	39	46	60	68	69	70	71	75
BM	91	83	68	55	50	34	26	23	19	18	14
UCB	5	5	4	6	5	6	6	8	11	11	11

allo-HCT indicates allogeneic hematopoietic cell transplantation; AML, acute myeloid leukemia; BM, bone marrow, CIBMTR, Center for International Blood and Marrow Transplant Research; CR, complete remission; CR1, first complete remission; CR2, second complete remission; PB, peripheral blood; RD, related donor; UCB, umbilical cord blood; and vURD, voluntary unrelated donor.

Adult defined as ≥ 18 years.

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