Patient characteristics
| Parameter . | Subgroup of patients . | |
|---|---|---|
| Donor . | No donor . | |
| Number | 326 | 599 |
| Median age, y (range) | 39 (15–55) | 39 (16–55) |
| Sex | ||
| Male | 163 | 296 |
| Female | 163 | 303 |
| FAB type, n (%) | ||
| M0 | 6 (2) | 18 (3) |
| M1 | 56 (17) | 118 (20) |
| M2 | 101 (31) | 160 (27) |
| M4 | 66 (20) | 139 (23) |
| M5 | 75 (23) | 124 (21) |
| M6 | 8 (3) | 21 (4) |
| M7 | 1 (0.5) | 2 (0.5) |
| Unknown | 13 (4) | 17 (3) |
| WBC count, × 109/L, n (%) | ||
| No more than 20 | 175 (54) | 316 (53) |
| 20–100 | 117 (36) | 212 (35) |
| More than 100 | 33 (10) | 71 (12) |
| Cytogenetic classification, n (%) | ||
| Favorable | 38 (12) | 84 (14) |
| Intermediate | 225 (69) | 382 (64) |
| Unfavorable | 36 (11) | 71 (12) |
| Unknown | 27 (8) | 62 (10) |
| Cycles to CR, n (%) | ||
| 1 | 221 (68) | 427 (71) |
| 2 | 105 (32) | 172 (29) |
| Prognostic risk category, n (%)* | ||
| Good | 32 (10) | 73 (12.1) |
| Intermediate | 178 (55) | 333 (56) |
| Poor | 116 (36) | 193 (32) |
| Parameter . | Subgroup of patients . | |
|---|---|---|
| Donor . | No donor . | |
| Number | 326 | 599 |
| Median age, y (range) | 39 (15–55) | 39 (16–55) |
| Sex | ||
| Male | 163 | 296 |
| Female | 163 | 303 |
| FAB type, n (%) | ||
| M0 | 6 (2) | 18 (3) |
| M1 | 56 (17) | 118 (20) |
| M2 | 101 (31) | 160 (27) |
| M4 | 66 (20) | 139 (23) |
| M5 | 75 (23) | 124 (21) |
| M6 | 8 (3) | 21 (4) |
| M7 | 1 (0.5) | 2 (0.5) |
| Unknown | 13 (4) | 17 (3) |
| WBC count, × 109/L, n (%) | ||
| No more than 20 | 175 (54) | 316 (53) |
| 20–100 | 117 (36) | 212 (35) |
| More than 100 | 33 (10) | 71 (12) |
| Cytogenetic classification, n (%) | ||
| Favorable | 38 (12) | 84 (14) |
| Intermediate | 225 (69) | 382 (64) |
| Unfavorable | 36 (11) | 71 (12) |
| Unknown | 27 (8) | 62 (10) |
| Cycles to CR, n (%) | ||
| 1 | 221 (68) | 427 (71) |
| 2 | 105 (32) | 172 (29) |
| Prognostic risk category, n (%)* | ||
| Good | 32 (10) | 73 (12.1) |
| Intermediate | 178 (55) | 333 (56) |
| Poor | 116 (36) | 193 (32) |
FAB indicates French-American-British classification; CR, complete remission; WBC, white blood cell.
*Based on cytogenetics, WBC count, and early or late attainment of CR (see “Patients, materials, and methods”).