Distribution of IPI and survival estimates in the 3 groups among the 1514 of 2451 patients for which blocks were available for construction of a TMA
| Analysis group . | All patients 4-year OS (95% CI) . | Age > 60 y No. of patients (%) . | IPI category low . | IPI category low/intermediate . | IPI category high/intermediate . | IPI category high . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | |||
| r-CHOP (n = 347) | 69% (64,74%) | 231 (67%) | 94 (27%) | 85% (75, 91%) | 80 (23%) | 80% (69, 87%) | 87 (25%) | 68% (57, 77%) | 86 (25%) | 45% (34, 55%) |
| c-CHOP (n = 289) | 55% (49, 61%) | 211 (73%) | 79 (27%) | 84% (73, 91%) | 63 (22%) | 63% (50, 74%) | 79 (27%) | 48% (37, 58%) | 68 (24%) | 26% (17, 37%) |
| e-CHOP (n = 878)* | 59% (55, 62%) | 411 (47%) | 428 (50%) | 76% (72, 80%) | 208 (25%) | 49% (42, 56%) | 142 (17%) | 40% (31, 48%) | 67 (8%) | 24% (15, 35%) |
| Analysis group . | All patients 4-year OS (95% CI) . | Age > 60 y No. of patients (%) . | IPI category low . | IPI category low/intermediate . | IPI category high/intermediate . | IPI category high . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | No. of patients (%) . | 4-year OS (95% CI) . | |||
| r-CHOP (n = 347) | 69% (64,74%) | 231 (67%) | 94 (27%) | 85% (75, 91%) | 80 (23%) | 80% (69, 87%) | 87 (25%) | 68% (57, 77%) | 86 (25%) | 45% (34, 55%) |
| c-CHOP (n = 289) | 55% (49, 61%) | 211 (73%) | 79 (27%) | 84% (73, 91%) | 63 (22%) | 63% (50, 74%) | 79 (27%) | 48% (37, 58%) | 68 (24%) | 26% (17, 37%) |
| e-CHOP (n = 878)* | 59% (55, 62%) | 411 (47%) | 428 (50%) | 76% (72, 80%) | 208 (25%) | 49% (42, 56%) | 142 (17%) | 40% (31, 48%) | 67 (8%) | 24% (15, 35%) |
Median follow-up was 4.4, 5.2, and 5.8 years among the r-CHOP, c-CHOP, and e-CHOP patients, respectively.
Thirty-three e-CHOP patients (4%) did not have IPI data.