Table 2

The production of IL-9 was decreased by a monoclonal anti–IL-2R-α antibody in ex vivo cultures of PBMCs from a patient with smoldering/chronic ATL

PBMC cultureIL-2 (pg/mL)
IL-9 (pg/mL)
Without anti–IL-2R-αWith anti–IL-2R-αWithout anti–IL-2R-αWith anti–IL-2R-α
Day 1 585 528 Not detected* Not detected* 
Day 2 954 957 46 Not detected* 
Day 3 1048 1170 146 Not detected* 
Day 4 1138 1424 196 Not detected* 
Day 5 1156 1633 287 Not detected* 
Day 6 1196 1704 532 Not detected* 
PBMC cultureIL-2 (pg/mL)
IL-9 (pg/mL)
Without anti–IL-2R-αWith anti–IL-2R-αWithout anti–IL-2R-αWith anti–IL-2R-α
Day 1 585 528 Not detected* Not detected* 
Day 2 954 957 46 Not detected* 
Day 3 1048 1170 146 Not detected* 
Day 4 1138 1424 196 Not detected* 
Day 5 1156 1633 287 Not detected* 
Day 6 1196 1704 532 Not detected* 

The data represent 2 independent experiments.

*

The level of IL-9 was < 1 pg/mL.

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