Patient demographics
Characteristics . | Values . |
---|---|
Total no. of patients | 41 |
Median age, y (range) | 34 (14-84) |
Sex, male/female | 25/16 |
Cause of AA | |
Idiopathic | 38 |
After hepatitis | 3 |
PNH clone (>1% GPI-AP deficient granulocytes) | 8 |
Time analysis | |
Patients at diagnosis | 21 |
Severe AA | 16 |
Moderate AA | 5 |
Patients in complete remission | 13 |
Anterior treatments | |
hATG + CSA | 9 |
rATG + CSA | 4 |
hATG + CSA + mycophenolate mofetil | 2 |
hATG + CSA + sirolimus | 1 |
Campath | 4 |
> 1 immunosuppressive courses | 3 |
Duration follow-up since last treatment, y; median (range) | 3 (1-7) |
Poor responders | 16 |
Anterior treatments | |
hATG + CSA | 15 |
rATG + CSA | 10 |
hATG + CSA + mycophenolate mofetil | 2 |
hATG + CSA + sirolimus | 1 |
Campath | 4 |
Daclizumab | 1 |
Alemtuzumab | 1 |
Androgens (Danazol) | 3 |
> 2 immunosuppressive courses | 12 |
Patients off therapy at time of sampling (yes/no) | 7/9 |
Transfusion status at time of sampling (yes/no) | 11/5 |
Characteristics . | Values . |
---|---|
Total no. of patients | 41 |
Median age, y (range) | 34 (14-84) |
Sex, male/female | 25/16 |
Cause of AA | |
Idiopathic | 38 |
After hepatitis | 3 |
PNH clone (>1% GPI-AP deficient granulocytes) | 8 |
Time analysis | |
Patients at diagnosis | 21 |
Severe AA | 16 |
Moderate AA | 5 |
Patients in complete remission | 13 |
Anterior treatments | |
hATG + CSA | 9 |
rATG + CSA | 4 |
hATG + CSA + mycophenolate mofetil | 2 |
hATG + CSA + sirolimus | 1 |
Campath | 4 |
> 1 immunosuppressive courses | 3 |
Duration follow-up since last treatment, y; median (range) | 3 (1-7) |
Poor responders | 16 |
Anterior treatments | |
hATG + CSA | 15 |
rATG + CSA | 10 |
hATG + CSA + mycophenolate mofetil | 2 |
hATG + CSA + sirolimus | 1 |
Campath | 4 |
Daclizumab | 1 |
Alemtuzumab | 1 |
Androgens (Danazol) | 3 |
> 2 immunosuppressive courses | 12 |
Patients off therapy at time of sampling (yes/no) | 7/9 |
Transfusion status at time of sampling (yes/no) | 11/5 |