Plaque phenotypic characteristics of established atherosclerosis
| . | Baseline . | Cd40l+/+Apoe−/− . | Cd40l−/−Apoe−/− . | Vehicle . |
|---|---|---|---|---|
| % CD3 | 0.2 ± 0.1 | 3.4 ± 0.6 | 3.4 ± 0.4 | 2.0 ± 0.4 |
| % CD45 | 2.9 ± 0.9 | 4.6 ± 0.8 | 5.2 ± 0.5 | 2.6 ± 0.2 |
| % Mac3 | 42.1 ± 6.6 | 44.5 ± 2.8 | 58.8 ± 5.1 | 62.5 ± 5.2 |
| MAC-3 Abs | 81.8 ± 38.6 | 385.6 ± 52.2 | 310.9 ± 63.8 | 363.5 ± 84.2 |
| Caspase-3+ | 0.1 ± 0.1 | 1.3 ± 0.3 | 1.4 ± 0.4 | 0.9 ± 0.3 |
| % α-SMA | 0.0 ± 0.0 | 11.3 ± 1.3 | 11.4 ± 1.0 | 11.0 ± 0.5 |
| % SR | 1.1 ± 0.9 | 34.2 ± 5.9 | 19.0 ± 5.6* | 23.2 ± 5.9 |
| % LC | 0.0 ± 0.0 | 7.9 ± 2.5 | 5.1 ± 1.5 | 3.7 ± 1.6 |
| . | Baseline . | Cd40l+/+Apoe−/− . | Cd40l−/−Apoe−/− . | Vehicle . |
|---|---|---|---|---|
| % CD3 | 0.2 ± 0.1 | 3.4 ± 0.6 | 3.4 ± 0.4 | 2.0 ± 0.4 |
| % CD45 | 2.9 ± 0.9 | 4.6 ± 0.8 | 5.2 ± 0.5 | 2.6 ± 0.2 |
| % Mac3 | 42.1 ± 6.6 | 44.5 ± 2.8 | 58.8 ± 5.1 | 62.5 ± 5.2 |
| MAC-3 Abs | 81.8 ± 38.6 | 385.6 ± 52.2 | 310.9 ± 63.8 | 363.5 ± 84.2 |
| Caspase-3+ | 0.1 ± 0.1 | 1.3 ± 0.3 | 1.4 ± 0.4 | 0.9 ± 0.3 |
| % α-SMA | 0.0 ± 0.0 | 11.3 ± 1.3 | 11.4 ± 1.0 | 11.0 ± 0.5 |
| % SR | 1.1 ± 0.9 | 34.2 ± 5.9 | 19.0 ± 5.6* | 23.2 ± 5.9 |
| % LC | 0.0 ± 0.0 | 7.9 ± 2.5 | 5.1 ± 1.5 | 3.7 ± 1.6 |
P < .05 vs Cd40l+/+Apoe−/−.