Table 2

Plaque phenotypic characteristics of collar-induced atherosclerosis

Cd40l+/+Apoe−/−Cd40l−/−Apoe−/−Vehicle
% CD3 5.9 ± 0.7 5.1 ± 1.0 4.0 ± 0.4 
% CD45 14.4 ± 2.3 15.6 ± 2.3 10.0 ± 1.8 
% Mac3 52.0 ± 1.4 46.1 ± 1.4* 52.7 ± 3.7 
MAC-3 Abs 121.0 ± 15.3 126.2 ± 11.7 118.6 ± 16.4 
Caspase-3+ 1.9 ± 0.2 1.2 ± 0.2* 1.0 ± 0.17 
% α-SMA 19.7 ± 6.0 15.5 ± 3.0* 12.1 ± 2 
% SR 43.9 ± 1.3 44.0 ± 2.9 52.4 ± 2.1 
% LC 14.3 ± 3.6 16.9 ± 3.2 17.4 ± 2.4 
Cd40l+/+Apoe−/−Cd40l−/−Apoe−/−Vehicle
% CD3 5.9 ± 0.7 5.1 ± 1.0 4.0 ± 0.4 
% CD45 14.4 ± 2.3 15.6 ± 2.3 10.0 ± 1.8 
% Mac3 52.0 ± 1.4 46.1 ± 1.4* 52.7 ± 3.7 
MAC-3 Abs 121.0 ± 15.3 126.2 ± 11.7 118.6 ± 16.4 
Caspase-3+ 1.9 ± 0.2 1.2 ± 0.2* 1.0 ± 0.17 
% α-SMA 19.7 ± 6.0 15.5 ± 3.0* 12.1 ± 2 
% SR 43.9 ± 1.3 44.0 ± 2.9 52.4 ± 2.1 
% LC 14.3 ± 3.6 16.9 ± 3.2 17.4 ± 2.4 
*

P < .05 vs Cd40l+/+Apoe−/−.

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