Experimental therapies for myelofibrosis with reported efficacy for symptomatic splenomegaly
| . | Anemia . | Splenomegaly . | Constitutional symptoms . | Pruritus . | Reference . |
|---|---|---|---|---|---|
| INCB018424 | < 10% | X | X | X | 43 |
| CEP-701 | < 10% | X | — | X | 47 |
| XL019 | — | X | X | X | 46 |
| TG101348 | — | X | X | X | 45 |
| ITF2357 | — | X | X | X | 48 |
| . | Anemia . | Splenomegaly . | Constitutional symptoms . | Pruritus . | Reference . |
|---|---|---|---|---|---|
| INCB018424 | < 10% | X | X | X | 43 |
| CEP-701 | < 10% | X | — | X | 47 |
| XL019 | — | X | X | X | 46 |
| TG101348 | — | X | X | X | 45 |
| ITF2357 | — | X | X | X | 48 |
— indicates not applicable; and X, instance.