Hematologic profile of Plt4/+ and Plt6/+ mutant mice
| . | Genotype . | ||
|---|---|---|---|
| +/+ . | Plt4/+ . | Plt6/+ . | |
| Peripheral blood (Advia) | n = 13 | n = 9 | n = 16 |
| Platelet count, ×109/L | 1093 ± 133 | 1157 ± 167 | 1166 ± 185 |
| Red cell count, ×1012/L | 10.9 ± 0.4 | 10.9 ± 0.3 | 10.8 ± 0.4 |
| Hematocrit, % | 49.6 ± 1.4 | 49.3 ± 1.2 | 50.2 ± 1.4 |
| White cell count, ×109/L | 9.9 ± 1.8 | 6.9 ± 2.5 | 8.8 ± 2.1 |
| Neutrophils | 0.90 ± 0.20 | 0.64 ± 0.26 | 0.93 ± 0.18 |
| Lymphocytes | 8.4 ± 1.6 | 5.8 ± 2.1 | 7.2 ± 1.9 |
| Monocytes | 0.12 ± 0.05 | 0.08 ± 0.04 | 0.11 ± 0.03 |
| Eosinophils | 0.19 ± 0.05 | 0.18 ± 0.07 | 0.23 ± 0.11 |
| Bone marrow | n = 4 | n = 4 | n = 4 |
| Megakaryocytes (per 10 hpf)* | 77 ± 9 | 87 ± 18 | 73 ± 12 |
| Spleen | n = 4 | n = 4 | n = 4 |
| Megakaryocytes (per 10 hpf)* | 20 ± 7 | 24 ± 18 | 49 ± 18 |
| . | Genotype . | ||
|---|---|---|---|
| +/+ . | Plt4/+ . | Plt6/+ . | |
| Peripheral blood (Advia) | n = 13 | n = 9 | n = 16 |
| Platelet count, ×109/L | 1093 ± 133 | 1157 ± 167 | 1166 ± 185 |
| Red cell count, ×1012/L | 10.9 ± 0.4 | 10.9 ± 0.3 | 10.8 ± 0.4 |
| Hematocrit, % | 49.6 ± 1.4 | 49.3 ± 1.2 | 50.2 ± 1.4 |
| White cell count, ×109/L | 9.9 ± 1.8 | 6.9 ± 2.5 | 8.8 ± 2.1 |
| Neutrophils | 0.90 ± 0.20 | 0.64 ± 0.26 | 0.93 ± 0.18 |
| Lymphocytes | 8.4 ± 1.6 | 5.8 ± 2.1 | 7.2 ± 1.9 |
| Monocytes | 0.12 ± 0.05 | 0.08 ± 0.04 | 0.11 ± 0.03 |
| Eosinophils | 0.19 ± 0.05 | 0.18 ± 0.07 | 0.23 ± 0.11 |
| Bone marrow | n = 4 | n = 4 | n = 4 |
| Megakaryocytes (per 10 hpf)* | 77 ± 9 | 87 ± 18 | 73 ± 12 |
| Spleen | n = 4 | n = 4 | n = 4 |
| Megakaryocytes (per 10 hpf)* | 20 ± 7 | 24 ± 18 | 49 ± 18 |
Data are mean plus or minus SD.
hpf indicates high-power field (×600 for bone marrow, ×200 for spleen).
Determined from histologic sections.