Table 1 Hematologic parameters of mice... | American Society of Hematology

Table 1

Hematologic parameters of mice carrying the conditional fII allele

	fII^WT	Mx⁻fII^lox/−	Mx⁺fII^lox/−	Mx⁻fII^lox/− poly I:C	Mx⁺fII^lox/− poly I:C
White blood cell count, ×10³/μL	1.2 ± 0.1	1.4 ± 0.3	1.4 ± 0.2	1.6 ± 0.3	1.0 ± 0.3
Hemoglobin, g/dL	12.1 ± 0.2	11.5 ± 0.3	11.9 ± 0.2	11.7 ± 0.4	11.5 ± 1.2
Platelet count, ×10³/μL	856 ± 19	780 ± 24	759 ± 43	828 ± 18	943 ± 87
Thrombin time, s	29.2 ± 0.6	26.5 ± 2.8	26.5 ± 0.5	25.2 ± 0.4	23.5 ± 0.8
Prothrombin time, s	10.3 ± 0.1	14.3 ± 0.1*	14.6 ± 0.3*	14.5 ± 0.7*	> 300†
Partial thromboplastin time, s	28.1 ± 0.4	44.8 ± 5*	52.1 ± 2.3*	43.8 ± 2.1*	> 300†

	fII^WT	Mx⁻fII^lox/−	Mx⁺fII^lox/−	Mx⁻fII^lox/− poly I:C	Mx⁺fII^lox/− poly I:C
White blood cell count, ×10³/μL	1.2 ± 0.1	1.4 ± 0.3	1.4 ± 0.2	1.6 ± 0.3	1.0 ± 0.3
Hemoglobin, g/dL	12.1 ± 0.2	11.5 ± 0.3	11.9 ± 0.2	11.7 ± 0.4	11.5 ± 1.2
Platelet count, ×10³/μL	856 ± 19	780 ± 24	759 ± 43	828 ± 18	943 ± 87
Thrombin time, s	29.2 ± 0.6	26.5 ± 2.8	26.5 ± 0.5	25.2 ± 0.4	23.5 ± 0.8
Prothrombin time, s	10.3 ± 0.1	14.3 ± 0.1*	14.6 ± 0.3*	14.5 ± 0.7*	> 300†
Partial thromboplastin time, s	28.1 ± 0.4	44.8 ± 5*	52.1 ± 2.3*	43.8 ± 2.1*	> 300†

P < .05 vs wild-type mice with the Mann-Whitney U test.

P < .05 vs wild-type mice with the Fisher exact test.