Relationship between del20q and JAK2 mutations
| . | del20q . | |||
|---|---|---|---|---|
| Absent (%) . | . | Present (%) . | Present (%) (Campbell et al13 ) . | |
| MPD (total 664) | 645 | 19 | 28 | |
| JAK2-V617F positive | 449 (70) | 14 (74) | 27 (96) | |
| JAK2-V617F negative | 196 (30) | 5 (26) | 1 (4) | |
| P = .805 | ||||
| ET (total 320) | 316 | 4 | 5 | |
| JAK2-V617F positive | 200 (63) | 4 (100) | 5 (100) | |
| JAK2-V617F negative | 116 (37) | 0 (0) | 0 (0) | |
| P = .3 | ||||
| PV (total 262) | 255 | 7 | 12 | |
| JAK2-V617F positive | 213 (84) | 6 (86) | 12 (100) | |
| JAK2 exon 12 | 5 (2) | 0 | ||
| JAK2-V617F/ exon 12 negative | 37 (14) | 1 (14) | 0 (0) | |
| P = 1 | ||||
| PMF (total 82) | 74 | 8 | 10 | |
| JAK2-V617F positive | 37 (50) | 4 (50) | 9 (90) | |
| JAK2-V617F negative | 37 (50) | 4 (50) | 1 (10) | |
| P = 1 | ||||
| . | del20q . | |||
|---|---|---|---|---|
| Absent (%) . | . | Present (%) . | Present (%) (Campbell et al13 ) . | |
| MPD (total 664) | 645 | 19 | 28 | |
| JAK2-V617F positive | 449 (70) | 14 (74) | 27 (96) | |
| JAK2-V617F negative | 196 (30) | 5 (26) | 1 (4) | |
| P = .805 | ||||
| ET (total 320) | 316 | 4 | 5 | |
| JAK2-V617F positive | 200 (63) | 4 (100) | 5 (100) | |
| JAK2-V617F negative | 116 (37) | 0 (0) | 0 (0) | |
| P = .3 | ||||
| PV (total 262) | 255 | 7 | 12 | |
| JAK2-V617F positive | 213 (84) | 6 (86) | 12 (100) | |
| JAK2 exon 12 | 5 (2) | 0 | ||
| JAK2-V617F/ exon 12 negative | 37 (14) | 1 (14) | 0 (0) | |
| P = 1 | ||||
| PMF (total 82) | 74 | 8 | 10 | |
| JAK2-V617F positive | 37 (50) | 4 (50) | 9 (90) | |
| JAK2-V617F negative | 37 (50) | 4 (50) | 1 (10) | |
| P = 1 | ||||
P values represent Fisher exact test.