Table 5
Comparison of 14-day versus 21-day tipifarnib administration
.
14 days (A)
.
21 days (B)
.
P
.
Toxicity, no. (%) of patients
Grade 3 mucositis
2/54 (4)
4/30 (13)
.18
Induction death
3/54 (6)
6/30 (20)
.06
Efficacy, day to begin cycle 2, median (range)
30 (29-43)
35 (29-46)
Complete remission, no. (%) of patients
16/54 (30)
5/30 (17)
.29
.
14 days (A)
.
21 days (B)
.
P
.
Toxicity, no. (%) of patients
Grade 3 mucositis
2/54 (4)
4/30 (13)
.18
Induction death
3/54 (6)
6/30 (20)
.06
Efficacy, day to begin cycle 2, median (range)
30 (29-43)
35 (29-46)
Complete remission, no. (%) of patients
16/54 (30)
5/30 (17)
.29
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